format-version: 1.2
date: 05:03:2008 16:39
auto-generated-by: ONTO-PERL
subsetdef: goslim_candida "Candida GO slim"
subsetdef: goslim_generic "Generic GO slim"
subsetdef: goslim_goa "GOA and proteome slim"
subsetdef: goslim_pir "PIR GO slim"
subsetdef: goslim_plant "Plant GO slim"
subsetdef: goslim_yeast "Yeast GO slim"
subsetdef: gosubset_prok "Prokaryotic GO subset"
synonymtypedef: systematic_synonym "Systematic synonym" EXACT
default-namespace: cellcycle_ontology_s_cerevisiae
remark: Merged ontology

[Term]
id: CCO:B0000000
name: core cell cycle protein
def: "A protein being considered as principal in the regulation of the cell cycle process" [CCO:cco_team]
is_a: CCO:U0000007 ! cell cycle protein

[Term]
id: CCO:B0000001
name: SEM1_YEAST
def: "26 proteasome complex subunit SEM1" [UniProtKB:O94742]
xref: EMBL:AAC96096.1
xref: EMBL:AAD08804.1
xref: EMBL:AAS56045.1
xref: UniProtKB:O94742
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002080 ! SEM1_yeast
relationship: located_in CCO:C0000252 ! nucleus
relationship: located_in CCO:C0000373 ! microsome
relationship: located_in CCO:C0000397 ! cytosol
relationship: located_in CCO:C0001750 ! protein complex
relationship: located_in CCO:C0002082 ! proteasome regulatory particle, lid subcomplex
relationship: participates_in CCO:I0003899 ! rpn1-rpn2 physical interaction
relationship: participates_in CCO:I0003900 ! rpn1-rpn2-1 physical interaction
relationship: participates_in CCO:P0000346 ! regulation of cell cycle

[Term]
id: CCO:B0000002
name: CDC28_YEAST
def: "Cell division control protein 28" [UniProtKB:P00546]
synonym: "EC 2.7.11.22" EXACT [UniProtKB:P00546]
xref: EMBL:CAA25065.1
xref: EMBL:CAA56509.1
xref: EMBL:CAA85119.1
xref: UniProtKB:P00546
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000286 ! CDC28_yeast
relationship: participates_in CCO:I0000695 ! cdc28-cln1-1 physical interaction
relationship: participates_in CCO:I0000696 ! cdc28-cak1-1 physical interaction
relationship: participates_in CCO:I0000697 ! cdc28-yif0 physical interaction
relationship: participates_in CCO:I0000698 ! cdc28-ykb4 physical interaction
relationship: participates_in CCO:I0000699 ! cdc28-cln3-1 physical interaction
relationship: participates_in CCO:I0000700 ! cdc28-q02606 physical interaction
relationship: participates_in CCO:I0000701 ! cdc28-stb1-1 physical interaction
relationship: participates_in CCO:I0000702 ! cdc28-yk57 physical interaction
relationship: participates_in CCO:I0000703 ! cdc28-yeo9 physical interaction
relationship: participates_in CCO:I0000704 ! cdc28-muk1-1 physical interaction
relationship: participates_in CCO:I0000705 ! cdc28-sog2 physical interaction
relationship: participates_in CCO:I0000706 ! cdc28-ym76 physical interaction
relationship: participates_in CCO:I0000707 ! cdc28-q08910 physical interaction
relationship: participates_in CCO:I0000708 ! cdc28-yni9 physical interaction
relationship: participates_in CCO:I0000709 ! cdc28-arp8 physical interaction
relationship: participates_in CCO:I0001061 ! cks1-cdc28 physical interaction
relationship: participates_in CCO:I0001067 ! cdc28-cks1 physical interaction
relationship: participates_in CCO:I0002080 ! cdc28-cak1 physical interaction
relationship: participates_in CCO:I0002081 ! cdc28-cln1 physical interaction
relationship: participates_in CCO:I0002082 ! cdc28-cln3 physical interaction
relationship: participates_in CCO:I0002083 ! cdc28-yer059w physical interaction
relationship: participates_in CCO:I0002084 ! cdc28-yil050w physical interaction
relationship: participates_in CCO:I0002085 ! cdc28-stb1 physical interaction
relationship: participates_in CCO:I0002086 ! cdc28-ykl014c physical interaction
relationship: participates_in CCO:I0002087 ! cdc28-ykr077w physical interaction
relationship: participates_in CCO:I0002088 ! cdc28-ypl014w physical interaction
relationship: participates_in CCO:I0002089 ! cdc28-muk1 physical interaction
relationship: participates_in CCO:I0002114 ! clb5-cdc28 physical interaction
relationship: participates_in CCO:I0002127 ! cln3-cdc28 physical interaction
relationship: participates_in CCO:I0002344 ! ga-58 physical interaction
relationship: participates_in CCO:I0002362 ! ga-78 physical interaction
relationship: participates_in CCO:I0002704 ! cks1-cdc28-1 physical interaction
relationship: participates_in CCO:I0002760 ! sic1-cdc28 physical interaction
relationship: participates_in CCO:I0002798 ! cdc28-asc1 physical interaction
relationship: participates_in CCO:I0003160 ! yk71-bmh1 physical interaction
relationship: participates_in CCO:I0003344 ! cdc28-cks1-1 physical interaction
relationship: participates_in CCO:I0004881 ! ho-55 physical interaction
relationship: participates_in CCO:I0004906 ! ho-93 physical interaction
relationship: participates_in CCO:I0004972 ! ho-209 physical interaction
relationship: participates_in CCO:I0005028 ! ho-315 physical interaction
relationship: participates_in CCO:I0005162 ! ho-561 physical interaction
relationship: participates_in CCO:I0005182 ! ho-597 physical interaction
relationship: participates_in CCO:I0005183 ! ho-598 physical interaction
relationship: participates_in CCO:I0005220 ! ho-687 physical interaction
relationship: participates_in CCO:I0005581 ! cdc28-9 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: participates_in CCO:P0000081 ! mitosis
relationship: participates_in CCO:P0000226 ! regulation of meiosis
relationship: transforms_into CCO:B0006788 ! CDC28_YEAST-Phosphothreonine18
relationship: transforms_into CCO:B0006789 ! CDC28_YEAST-Phosphotyrosine19
relationship: transforms_into CCO:B0006790 ! CDC28_YEAST-Phosphothreonine169

[Term]
id: CCO:B0000003
name: TBB_YEAST
def: "Tubulin beta chain" [UniProtKB:P02557]
synonym: "Beta-tubulin" EXACT [UniProtKB:P02557]
xref: EMBL:BAA09202.1
xref: EMBL:CAA24603.1
xref: EMBL:CAA25035.1
xref: UniProtKB:P02557
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002373 ! TUB2_yeast
relationship: located_in CCO:C0000324 ! cytoplasm
relationship: located_in CCO:C0000386 ! spindle pole body
relationship: located_in CCO:C0000395 ! polar microtubule
relationship: located_in CCO:C0000396 ! kinetochore microtubule
relationship: located_in CCO:C0000434 ! microtubule
relationship: located_in CCO:C0000438 ! nuclear microtubule
relationship: located_in CCO:C0000439 ! cytoplasmic microtubule
relationship: located_in CCO:C0001750 ! protein complex
relationship: participates_in CCO:I0001319 ! ser3-tub2 physical interaction
relationship: participates_in CCO:I0002573 ! tfb3-mpg1 physical interaction
relationship: participates_in CCO:I0002576 ! kap95-gcn1 physical interaction
relationship: participates_in CCO:I0002579 ! gcn1-aac2 physical interaction
relationship: participates_in CCO:I0002581 ! sec16-adh1 physical interaction
relationship: participates_in CCO:I0002582 ! dom34-eft1 physical interaction
relationship: participates_in CCO:I0002595 ! rgd1-rpl17b physical interaction
relationship: participates_in CCO:I0002604 ! ym52-mcm5 physical interaction
relationship: participates_in CCO:I0002608 ! yg5y-rpl4b physical interaction
relationship: participates_in CCO:I0002611 ! pdr12-adh1 physical interaction
relationship: participates_in CCO:I0002618 ! fth1-adh1 physical interaction
relationship: participates_in CCO:I0002619 ! mae1-aro1 physical interaction
relationship: participates_in CCO:I0002631 ! ymb8-atp2 physical interaction
relationship: participates_in CCO:I0002632 ! vap1-hsp42 physical interaction
relationship: participates_in CCO:I0002633 ! yjg2-ssa1 physical interaction
relationship: participates_in CCO:I0002639 ! abp140-act1 physical interaction
relationship: participates_in CCO:I0002643 ! wtm1-hsp60 physical interaction
relationship: participates_in CCO:I0002645 ! vid27-adh1 physical interaction
relationship: participates_in CCO:I0002648 ! zrc1-gcn1 physical interaction
relationship: participates_in CCO:I0002649 ! nog2-aro1 physical interaction
relationship: participates_in CCO:I0002650 ! sua7-ded1 physical interaction
relationship: participates_in CCO:I0002655 ! gdh1-adh1 physical interaction
relationship: participates_in CCO:I0002658 ! sks1-hsp42 physical interaction
relationship: participates_in CCO:I0002660 ! ape2-aco1 physical interaction
relationship: participates_in CCO:I0002662 ! ykg5-adh1 physical interaction
relationship: participates_in CCO:I0002666 ! nan1-imp3 physical interaction
relationship: participates_in CCO:I0002667 ! mft1-adh1 physical interaction
relationship: participates_in CCO:I0002668 ! sec27-mpg1 physical interaction
relationship: participates_in CCO:I0002670 ! faa4-aco1 physical interaction
relationship: participates_in CCO:I0002671 ! ole1-anp1 physical interaction
relationship: participates_in CCO:I0002673 ! brx1-dbp10 physical interaction
relationship: participates_in CCO:I0002675 ! hmg1-adh1 physical interaction
relationship: participates_in CCO:I0002684 ! acs2-asc1 physical interaction
relationship: participates_in CCO:I0002685 ! yn53-atp2 physical interaction
relationship: participates_in CCO:I0002698 ! ald4-mpg1 physical interaction
relationship: participates_in CCO:I0002702 ! ade5,7-mpg1 physical interaction
relationship: participates_in CCO:I0002707 ! tsc13-bni1 physical interaction
relationship: participates_in CCO:I0002708 ! sec2-act1 physical interaction
relationship: participates_in CCO:I0002711 ! erd2-bni1 physical interaction
relationship: participates_in CCO:I0002713 ! ald5-hsp60 physical interaction
relationship: participates_in CCO:I0002724 ! rad25-imd3 physical interaction
relationship: participates_in CCO:I0002725 ! q12029-adh1 physical interaction
relationship: participates_in CCO:I0002728 ! yhm2-adh1 physical interaction
relationship: participates_in CCO:I0002738 ! ygk7-atp2 physical interaction
relationship: participates_in CCO:I0002739 ! pmr1-anp1 physical interaction
relationship: participates_in CCO:I0002741 ! kap114-htb1 physical interaction
relationship: participates_in CCO:I0002744 ! phb1-mpg1 physical interaction
relationship: participates_in CCO:I0002746 ! pyk2-mpg1 physical interaction
relationship: participates_in CCO:I0002753 ! yj42-cct2 physical interaction
relationship: participates_in CCO:I0002754 ! not5-mpg1 physical interaction
relationship: participates_in CCO:I0002774 ! puf3-mpg1 physical interaction
relationship: participates_in CCO:I0002776 ! pim1-idh2 physical interaction
relationship: participates_in CCO:I0002777 ! sur2-rpl10 physical interaction
relationship: participates_in CCO:I0002790 ! met7-gfa1 physical interaction
relationship: participates_in CCO:I0002792 ! phb2-act1 physical interaction
relationship: participates_in CCO:I0002795 ! npr1-act1 physical interaction
relationship: participates_in CCO:I0002798 ! cdc28-asc1 physical interaction
relationship: participates_in CCO:I0002799 ! rfc4-chl12 physical interaction
relationship: participates_in CCO:I0002804 ! erg13-act1 physical interaction
relationship: participates_in CCO:I0002807 ! ubp3-bre5 physical interaction
relationship: participates_in CCO:I0002808 ! ymf5-adh1 physical interaction
relationship: participates_in CCO:I0002816 ! yij0-adh1-1 physical interaction
relationship: participates_in CCO:I0002818 ! cdc54-mpg1 physical interaction
relationship: participates_in CCO:I0002821 ! erg25-ade5,7 physical interaction
relationship: participates_in CCO:I0002822 ! rpl23a-bcp1 physical interaction
relationship: participates_in CCO:I0002824 ! ubp1-adh1 physical interaction
relationship: participates_in CCO:I0002826 ! glc7-ade16 physical interaction
relationship: participates_in CCO:I0002832 ! ecm30-ssa1 physical interaction
relationship: participates_in CCO:I0002838 ! mak21-brx1 physical interaction
relationship: participates_in CCO:I0002839 ! rpa2-gcd6 physical interaction
relationship: participates_in CCO:I0002841 ! dpm1-kar2 physical interaction
relationship: participates_in CCO:I0002844 ! rer2-rpl4b physical interaction
relationship: participates_in CCO:I0002845 ! ym44-atp2 physical interaction
relationship: participates_in CCO:I0002850 ! car1-cdc60 physical interaction
relationship: participates_in CCO:I0002853 ! dbp8-eft1 physical interaction
relationship: participates_in CCO:I0002860 ! cdc73-cka1 physical interaction
relationship: participates_in CCO:I0002868 ! sec39-adh1 physical interaction
relationship: participates_in CCO:I0002870 ! rad3-asc1 physical interaction
relationship: participates_in CCO:I0002872 ! rvs167-ecm29 physical interaction
relationship: participates_in CCO:I0002879 ! ski2-pyk1 physical interaction
relationship: participates_in CCO:I0002883 ! dcp1-dcp2 physical interaction
relationship: participates_in CCO:I0002889 ! pir1-elp3 physical interaction
relationship: participates_in CCO:I0002890 ! cdc16-apc1-1 physical interaction
relationship: participates_in CCO:I0002906 ! arp1-tef1 physical interaction
relationship: participates_in CCO:I0002907 ! hxt4-adh1 physical interaction
relationship: participates_in CCO:I0002911 ! pro3-ssa1 physical interaction
relationship: participates_in CCO:I0002912 ! emp24-adh1 physical interaction
relationship: participates_in CCO:I0002916 ! if2p-cbf5 physical interaction
relationship: participates_in CCO:I0002918 ! kel1-bem2 physical interaction
relationship: participates_in CCO:I0002924 ! ric1-mpg1 physical interaction
relationship: participates_in CCO:I0002928 ! aro1-cct8 physical interaction
relationship: participates_in CCO:I0002932 ! cmk1-aac2 physical interaction
relationship: participates_in CCO:I0002933 ! asp1-cdc48 physical interaction
relationship: participates_in CCO:I0002934 ! yka8-aac2 physical interaction
relationship: participates_in CCO:I0002937 ! omp2-eft1 physical interaction
relationship: participates_in CCO:I0002940 ! rpl18a-arx1 physical interaction
relationship: participates_in CCO:I0002942 ! yg3y-ded1 physical interaction
relationship: participates_in CCO:I0002945 ! mds3-cdc25 physical interaction
relationship: participates_in CCO:I0002947 ! his4-dhh1 physical interaction
relationship: participates_in CCO:I0002948 ! hrb1-asc1 physical interaction
relationship: participates_in CCO:I0002951 ! mkk1-grh1 physical interaction
relationship: participates_in CCO:I0002953 ! siw14-eft1 physical interaction
relationship: participates_in CCO:I0002956 ! ymh2-adh1 physical interaction
relationship: participates_in CCO:I0002965 ! rix7-ded1 physical interaction
relationship: participates_in CCO:I0002966 ! spt5-eft1 physical interaction
relationship: participates_in CCO:I0002982 ! cdc45-mpg1 physical interaction
relationship: participates_in CCO:I0002988 ! sec15-atp2 physical interaction
relationship: participates_in CCO:I0002992 ! vps4-bro1 physical interaction
relationship: participates_in CCO:I0002995 ! ycp4-act1 physical interaction
relationship: participates_in CCO:I0003009 ! met18-aro1 physical interaction
relationship: participates_in CCO:I0003010 ! nip7-arx1 physical interaction
relationship: participates_in CCO:I0003012 ! yg1i-act1 physical interaction
relationship: participates_in CCO:I0003016 ! hsp42-gln1 physical interaction
relationship: participates_in CCO:I0003022 ! pda2-kar2 physical interaction
relationship: participates_in CCO:I0003024 ! apl4-adh1 physical interaction
relationship: participates_in CCO:I0003026 ! tos1-eft1 physical interaction
relationship: participates_in CCO:I0003029 ! fas3-cct5 physical interaction
relationship: participates_in CCO:I0003031 ! nmd5-gcn1 physical interaction
relationship: participates_in CCO:I0003040 ! yj92-act1 physical interaction
relationship: participates_in CCO:I0003046 ! ecm17-hsc82 physical interaction
relationship: participates_in CCO:I0003049 ! chc1-clc1 physical interaction
relationship: participates_in CCO:I0003051 ! ilv3-aco1 physical interaction
relationship: participates_in CCO:I0003064 ! thi3-cct2 physical interaction
relationship: participates_in CCO:I0003071 ! mpg1-cct8 physical interaction
relationship: participates_in CCO:I0003074 ! enp1-cbf5 physical interaction
relationship: participates_in CCO:I0003086 ! nce102-adh1 physical interaction
relationship: participates_in CCO:I0003088 ! apc5-adh1 physical interaction
relationship: participates_in CCO:I0003096 ! ssk1-act1 physical interaction
relationship: participates_in CCO:I0003101 ! yeh1-kap123 physical interaction
relationship: participates_in CCO:I0003108 ! cdc9-mpg1 physical interaction
relationship: participates_in CCO:I0003112 ! smi1-act1 physical interaction
relationship: participates_in CCO:I0003113 ! ixr1-abf2 physical interaction
relationship: participates_in CCO:I0003121 ! ynr5-arx1 physical interaction
relationship: participates_in CCO:I0003122 ! cse1-rpp0 physical interaction
relationship: participates_in CCO:I0003123 ! ded81-cct4 physical interaction
relationship: participates_in CCO:I0003127 ! gsf2-mpg1 physical interaction
relationship: participates_in CCO:I0003137 ! uba1-gfa1 physical interaction
relationship: participates_in CCO:I0003141 ! yeu3-tub1 physical interaction
relationship: participates_in CCO:I0003143 ! ubp15-apl6 physical interaction
relationship: participates_in CCO:I0003149 ! mcm5-gcn20 physical interaction
relationship: participates_in CCO:I0003153 ! msn5-adh1 physical interaction
relationship: participates_in CCO:I0003156 ! gpt2-adh1 physical interaction
relationship: participates_in CCO:I0003170 ! yn86-adh1 physical interaction
relationship: participates_in CCO:I0003176 ! crd1-ded81 physical interaction
relationship: participates_in CCO:I0003177 ! apa1-aap1 physical interaction
relationship: participates_in CCO:I0003185 ! ilv2-dnm1 physical interaction
relationship: participates_in CCO:I0003191 ! mrs4-aac2 physical interaction
relationship: participates_in CCO:I0003196 ! skn7-gfa1 physical interaction
relationship: participates_in CCO:I0003203 ! mct1-hsp60 physical interaction
relationship: participates_in CCO:I0003207 ! cog8-cog1 physical interaction
relationship: participates_in CCO:I0003213 ! mdn1-mpg1 physical interaction
relationship: participates_in CCO:I0003214 ! pdr6-atp2 physical interaction
relationship: participates_in CCO:I0003237 ! cct7-act1 physical interaction
relationship: participates_in CCO:I0003239 ! srp54-bem2 physical interaction
relationship: participates_in CCO:I0003245 ! gcd7-aro1 physical interaction
relationship: participates_in CCO:I0003247 ! rad16-adh1 physical interaction
relationship: participates_in CCO:I0003249 ! nup2-adh1 physical interaction
relationship: participates_in CCO:I0003250 ! sln1-adh1 physical interaction
relationship: participates_in CCO:I0003251 ! nop58-dhr1 physical interaction
relationship: participates_in CCO:I0003252 ! ret2-gpt2 physical interaction
relationship: participates_in CCO:I0003253 ! vid24-eft1 physical interaction
relationship: participates_in CCO:I0003257 ! pdr15-aap1 physical interaction
relationship: participates_in CCO:I0003259 ! yij4-eft1 physical interaction
relationship: participates_in CCO:I0003269 ! ufe1-adh1 physical interaction
relationship: participates_in CCO:I0003277 ! yjg5-atp2 physical interaction
relationship: participates_in CCO:I0003282 ! hhf1-cpa1 physical interaction
relationship: participates_in CCO:I0003285 ! cka1-cka2 physical interaction
relationship: participates_in CCO:I0003301 ! dbp6-adh1 physical interaction
relationship: participates_in CCO:I0003302 ! yoj8-eft1 physical interaction
relationship: participates_in CCO:I0003303 ! ald2-ssa2 physical interaction
relationship: participates_in CCO:I0003305 ! swi6-mpg1 physical interaction
relationship: participates_in CCO:I0003306 ! ym8x-aro1 physical interaction
relationship: participates_in CCO:I0003307 ! hmg1-hmg2 physical interaction
relationship: participates_in CCO:I0003310 ! snl1-gls1 physical interaction
relationship: participates_in CCO:I0003313 ! ybp1-hhf1 physical interaction
relationship: participates_in CCO:I0003314 ! fpr4-arx1 physical interaction
relationship: participates_in CCO:I0003316 ! rna12-adh1 physical interaction
relationship: participates_in CCO:I0003319 ! dos2-gcn1 physical interaction
relationship: participates_in CCO:I0003320 ! med1-ada2 physical interaction
relationship: participates_in CCO:I0003322 ! nog1-erb1 physical interaction
relationship: participates_in CCO:I0003326 ! ste2-cdc48 physical interaction
relationship: participates_in CCO:I0003333 ! glt1-eft1 physical interaction
relationship: participates_in CCO:I0003339 ! erd2-brr2 physical interaction
relationship: participates_in CCO:I0003344 ! cdc28-cks1-1 physical interaction
relationship: participates_in CCO:I0003345 ! sly41-adh1 physical interaction
relationship: participates_in CCO:I0003348 ! gcd11-cdc123 physical interaction
relationship: participates_in CCO:I0003354 ! rpo41-ssb1 physical interaction
relationship: participates_in CCO:I0003356 ! ybv1-hsp42 physical interaction
relationship: participates_in CCO:I0003360 ! utp15-gcn1 physical interaction
relationship: participates_in CCO:I0003363 ! cbf5-cpa2 physical interaction
relationship: participates_in CCO:I0003367 ! tif32-hcr1 physical interaction
relationship: participates_in CCO:I0003369 ! pic2-ecm29 physical interaction
relationship: participates_in CCO:I0003376 ! yor29_10-adh1 physical interaction
relationship: participates_in CCO:I0003380 ! ape2-atp2 physical interaction
relationship: participates_in CCO:I0003383 ! yn28-ccr4 physical interaction
relationship: participates_in CCO:I0003388 ! ptm1-anp1 physical interaction
relationship: participates_in CCO:I0003391 ! dnm1-pab1 physical interaction
relationship: participates_in CCO:I0003392 ! yeb5-dcp1-1 physical interaction
relationship: participates_in CCO:I0003393 ! trp3-aha1 physical interaction
relationship: participates_in CCO:I0003399 ! lcb2-bmh1 physical interaction
relationship: participates_in CCO:I0003400 ! gcd2-gcd1 physical interaction
relationship: participates_in CCO:I0003405 ! nif3-gfa1 physical interaction
relationship: participates_in CCO:I0003417 ! ymc2-hsp60 physical interaction
relationship: participates_in CCO:I0003428 ! msf1-kap123 physical interaction
relationship: participates_in CCO:I0003429 ! erg26-mdn1 physical interaction
relationship: participates_in CCO:I0003434 ! sap185-atp2 physical interaction
relationship: participates_in CCO:I0003440 ! rrp5-adh1 physical interaction
relationship: participates_in CCO:I0003444 ! elo3-adh1 physical interaction
relationship: participates_in CCO:I0003445 ! fal1-bni1 physical interaction
relationship: participates_in CCO:I0003446 ! ndi1-gcn1 physical interaction
relationship: participates_in CCO:I0003453 ! adh3-aco1 physical interaction
relationship: participates_in CCO:I0003455 ! arp7-act1 physical interaction
relationship: participates_in CCO:I0003457 ! q05881-adh1-1 physical interaction
relationship: participates_in CCO:I0003462 ! ymp0-ssa2 physical interaction
relationship: participates_in CCO:I0003463 ! gcd7-ala1 physical interaction
relationship: participates_in CCO:I0003466 ! ald6-eft1 physical interaction
relationship: participates_in CCO:I0003467 ! yn8h-act1-1 physical interaction
relationship: participates_in CCO:I0003474 ! aha1-aro1 physical interaction
relationship: participates_in CCO:I0003480 ! alg12-aco1 physical interaction
relationship: participates_in CCO:I0003483 ! ura7-cpa2 physical interaction
relationship: participates_in CCO:I0003492 ! pho86-aco1 physical interaction
relationship: participates_in CCO:I0003495 ! hom2-aro1 physical interaction
relationship: participates_in CCO:I0003498 ! puf4-mpg1 physical interaction
relationship: participates_in CCO:I0003505 ! yb01-ssa2 physical interaction
relationship: participates_in CCO:I0003508 ! gcn3-cct4 physical interaction
relationship: participates_in CCO:I0003515 ! tub3-atp2 physical interaction
relationship: participates_in CCO:I0003519 ! nam9-gcn20 physical interaction
relationship: participates_in CCO:I0003521 ! prps3-eft1 physical interaction
relationship: participates_in CCO:I0003523 ! yew4-atp2 physical interaction
relationship: participates_in CCO:I0003530 ! ytm1-dbp10 physical interaction
relationship: participates_in CCO:I0003531 ! yml6-ded1 physical interaction
relationship: participates_in CCO:I0003534 ! nmd4-adh1 physical interaction
relationship: participates_in CCO:I0003536 ! rpl23a-bcp1-1 physical interaction
relationship: participates_in CCO:I0003537 ! ufd4-aha1 physical interaction
relationship: participates_in CCO:I0003540 ! smp2-pyk1 physical interaction
relationship: participates_in CCO:I0003546 ! nup192-adh1 physical interaction
relationship: participates_in CCO:I0003548 ! nup188-adh1 physical interaction
relationship: participates_in CCO:I0003568 ! yeo9-atp2 physical interaction
relationship: participates_in CCO:I0003570 ! scs7-cdc48 physical interaction
relationship: participates_in CCO:I0003577 ! phb2-ecm29 physical interaction
relationship: participates_in CCO:I0003579 ! xpo1-gcn1 physical interaction
relationship: participates_in CCO:I0003584 ! kap104-ecm29 physical interaction
relationship: participates_in CCO:I0003587 ! ymg9-cdc68 physical interaction
relationship: participates_in CCO:I0003588 ! rgr1-cse2 physical interaction
relationship: participates_in CCO:I0003592 ! idh2-idh1 physical interaction
relationship: participates_in CCO:I0003609 ! smi1-adh1-1 physical interaction
relationship: participates_in CCO:I0003617 ! yjo8-adh1 physical interaction
relationship: participates_in CCO:I0003619 ! pse1-dbp9 physical interaction
relationship: participates_in CCO:I0003620 ! rvb2-asc1 physical interaction
relationship: participates_in CCO:I0003622 ! yhb1-mpg1 physical interaction
relationship: participates_in CCO:I0003625 ! svl3-atp2 physical interaction
relationship: participates_in CCO:I0003626 ! snx41-gcn1 physical interaction
relationship: participates_in CCO:I0003628 ! cpa2-cpa1 physical interaction
relationship: participates_in CCO:I0003646 ! rpb6-gfa1 physical interaction
relationship: participates_in CCO:I0003648 ! sec16-aco1 physical interaction
relationship: participates_in CCO:I0003651 ! fur1-kar2 physical interaction
relationship: participates_in CCO:I0003848 ! aut2-tub2 physical interaction
relationship: participates_in CCO:I0003908 ! gcn5-ada2-2 physical interaction
relationship: participates_in CCO:I0003915 ! dbf2-adh5 physical interaction
relationship: participates_in CCO:I0003922 ! pho4-ade16 physical interaction
relationship: participates_in CCO:I0003929 ! gcn5-ade3 physical interaction
relationship: participates_in CCO:I0003943 ! tim50-aac2 physical interaction
relationship: participates_in CCO:I0003948 ! yn53-aof1001 physical interaction
relationship: participates_in CCO:I0003951 ! ykt5-aac2 physical interaction
relationship: participates_in CCO:I0004755 ! rbl2-tub2 physical interaction
relationship: participates_in CCO:I0005472 ! atp2-6 physical interaction
relationship: participates_in CCO:I0005478 ! cct2-10 physical interaction
relationship: participates_in CCO:I0005524 ! ded1-5 physical interaction
relationship: participates_in CCO:I0005535 ! aap1-38 physical interaction
relationship: participates_in CCO:I0005561 ! aha1-16 physical interaction
relationship: participates_in CCO:I0005562 ! gfa1-4 physical interaction
relationship: participates_in CCO:I0005576 ! aha1-8 physical interaction
relationship: participates_in CCO:I0005594 ! erg26-3 physical interaction
relationship: participates_in CCO:I0005614 ! aac2-25 physical interaction
relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation
relationship: participates_in CCO:P0000239 ! homologous chromosome segregation

[Term]
id: CCO:B0000004
name: TOP1_YEAST
def: "DNA topoisomerase 1" [UniProtKB:P04786]
synonym: "DNA topoisomerase I" EXACT [UniProtKB:P04786]
synonym: "EC 5.99.1.2" EXACT [UniProtKB:P04786]
synonym: "Maintenance of killer protein 1" EXACT [UniProtKB:P04786]
xref: EMBL:AAA35162.1
xref: EMBL:CAA99005.1
xref: UniProtKB:P04786
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002439 ! TOP1_yeast
relationship: participates_in CCO:I0001098 ! matalpha2-top1 physical interaction
relationship: participates_in CCO:I0001732 ! rif2-top1 physical interaction
relationship: participates_in CCO:I0001898 ! top1-ymr233w physical interaction
relationship: participates_in CCO:I0001899 ! top1-ynl099c physical interaction
relationship: participates_in CCO:I0002394 ! ga-175 physical interaction
relationship: participates_in CCO:I0002466 ! ga-326 physical interaction
relationship: participates_in CCO:I0002479 ! ga-352 physical interaction
relationship: participates_in CCO:I0002596 ! htb2-dpb2 physical interaction
relationship: participates_in CCO:I0003114 ! reb1-ade5,7 physical interaction
relationship: participates_in CCO:I0003378 ! abf2-act1 physical interaction
relationship: participates_in CCO:I0003510 ! rpd3-cka1 physical interaction
relationship: participates_in CCO:I0004633 ! top1-ymr233w-1 physical interaction
relationship: participates_in CCO:I0005243 ! ho-732 physical interaction
relationship: participates_in CCO:I0005392 ! abf2-21 physical interaction
relationship: participates_in CCO:I0005398 ! abf2-34 physical interaction
relationship: participates_in CCO:I0005467 ! brx1-16 physical interaction
relationship: participates_in CCO:I0005507 ! abf2-9 physical interaction
relationship: participates_in CCO:I0005515 ! ade5,7-8 physical interaction
relationship: participates_in CCO:I0005560 ! abf2-7 physical interaction
relationship: participates_in CCO:I0005618 ! chl12-19 physical interaction
relationship: participates_in CCO:I0005622 ! abf2-42 physical interaction
relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation
relationship: transforms_into CCO:B0009653 ! TOP1_YEAST-Phosphoserine14
relationship: transforms_into CCO:B0009654 ! TOP1_YEAST-Phosphoserine15
relationship: transforms_into CCO:B0009655 ! TOP1_YEAST-Phosphoserine49
relationship: transforms_into CCO:B0009656 ! TOP1_YEAST-Phosphoserine76

[Term]
id: CCO:B0000005
name: DNLI_YEAST
def: "DNA ligase I, mitochondrial precursor" [UniProtKB:P04819]
synonym: "EC 6.5.1.1" EXACT [UniProtKB:P04819]
synonym: "Polydeoxyribonucleotide synthase [ATP]" EXACT [UniProtKB:P04819]
xref: EMBL:AAU09681.1
xref: EMBL:CAA27005.1
xref: EMBL:CAA48158.1
xref: EMBL:CAA91582.1
xref: EMBL:CAA98737.1
xref: UniProtKB:P04819
xref: UniProtKB:Q12736
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000489 ! CDC9_yeast
relationship: participates_in CCO:I0001490 ! stb5-cdc9 physical interaction
relationship: participates_in CCO:I0003108 ! cdc9-mpg1 physical interaction
relationship: participates_in CCO:I0004732 ! abp1-cdc9 direct interaction
relationship: participates_in CCO:I0004903 ! ho-86 physical interaction
relationship: participates_in CCO:P0000038 ! mitotic cell cycle
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: transforms_into CCO:B0007002 ! DNLI_YEAST-Phosphoserine58
relationship: transforms_into CCO:B0007003 ! DNLI_YEAST-Phosphoserine75

[Term]
id: CCO:B0000006
name: CDC25_YEAST
def: "Cell division control protein 25" [UniProtKB:P04821]
xref: EMBL:AAA34478.1
xref: EMBL:AAB64528.1
xref: EMBL:AAB67360.1
xref: EMBL:CAA27259.1
xref: UniProtKB:P04821
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000283 ! CDC25_yeast
relationship: participates_in CCO:I0002500 ! ga-396 physical interaction
relationship: participates_in CCO:I0002544 ! ga-518 physical interaction
relationship: participates_in CCO:I0002628 ! yhm4-asc1 physical interaction
relationship: participates_in CCO:I0002945 ! mds3-cdc25 physical interaction
relationship: participates_in CCO:I0003115 ! yb75-cdc25 physical interaction
relationship: participates_in CCO:I0003174 ! pph1-avt4 physical interaction
relationship: participates_in CCO:I0003434 ! sap185-atp2 physical interaction
relationship: participates_in CCO:I0003941 ! ymc3-apn2 physical interaction
relationship: participates_in CCO:I0003945 ! cwc2-atp7 physical interaction
relationship: participates_in CCO:I0004780 ! cdc25-bnr1 physical interaction
relationship: participates_in CCO:I0004781 ! cdc25-nfi1 physical interaction
relationship: participates_in CCO:I0004782 ! cdc25-yby0 physical interaction
relationship: participates_in CCO:I0004783 ! cdc25-rsm19 physical interaction
relationship: participates_in CCO:I0004854 ! ho-3 physical interaction
relationship: participates_in CCO:I0005171 ! ho-575 physical interaction
relationship: participates_in CCO:I0005408 ! ade5,7-40 physical interaction
relationship: participates_in CCO:I0005410 ! cct2-12 physical interaction
relationship: participates_in CCO:I0005449 ! bem2-18 physical interaction
relationship: participates_in CCO:I0005523 ! bem2-21 physical interaction
relationship: participates_in CCO:I0005543 ! bem2-15 physical interaction
relationship: participates_in CCO:I0005677 ! bnr1-cdc25 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: participates_in CCO:P0000081 ! mitosis
relationship: participates_in CCO:P0000100 ! traversing start control point of mitotic cell cycle
relationship: participates_in CCO:P0000346 ! regulation of cell cycle
relationship: transforms_into CCO:B0006785 ! CDC25_YEAST-Phosphoserine151
relationship: transforms_into CCO:B0006786 ! CDC25_YEAST-Phosphoserine154
relationship: transforms_into CCO:B0006787 ! CDC25_YEAST-Phosphothreonine635

[Term]
id: CCO:B0000007
name: NOT2_YEAST
def: "General negative regulator of transcription subunit 2" [UniProtKB:P06100]
xref: EMBL:AAS55970.1
xref: EMBL:CAA27006.1
xref: EMBL:CAA27835.1
xref: EMBL:CAA48160.1
xref: EMBL:CAA91581.1
xref: EMBL:CAA98739.1
xref: UniProtKB:P06100
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0001312 ! NOT2_yeast
relationship: located_in CCO:C0000252 ! nucleus
relationship: located_in CCO:C0000324 ! cytoplasm
relationship: located_in CCO:C0000931 ! CCR4-NOT core complex
relationship: participates_in CCO:I0000531 ! d9461_23-not2 physical interaction
relationship: participates_in CCO:I0000550 ! yg1w-not2 physical interaction
relationship: participates_in CCO:I0000685 ! yj42-not2 physical interaction
relationship: participates_in CCO:I0000719 ! gic2-not2 physical interaction
relationship: participates_in CCO:I0000744 ! gic1-not2 physical interaction
relationship: participates_in CCO:I0000762 ! vps5-not2 physical interaction
relationship: participates_in CCO:I0001002 ! yjo7-not2 physical interaction
relationship: participates_in CCO:I0001004 ! sog2-not2 physical interaction
relationship: participates_in CCO:I0001383 ! soh1-not2 physical interaction
relationship: participates_in CCO:I0001498 ! cap2-not2 physical interaction
relationship: participates_in CCO:I0001567 ! ykl002w-not2 physical interaction
relationship: participates_in CCO:I0001594 ! ylr125w-not2 physical interaction
relationship: participates_in CCO:I0002347 ! ga-61 physical interaction
relationship: participates_in CCO:I0002653 ! mrd1-cct4 physical interaction
relationship: participates_in CCO:I0002754 ! not5-mpg1 physical interaction
relationship: participates_in CCO:I0002972 ! not2-not5 physical interaction
relationship: participates_in CCO:I0003255 ! not2-atp11 physical interaction
relationship: participates_in CCO:I0004493 ! msb2-not2 physical interaction
relationship: participates_in CCO:I0005226 ! ho-696 physical interaction
relationship: participates_in CCO:I0005547 ! mrd1-5 physical interaction
relationship: participates_in CCO:P0000346 ! regulation of cell cycle

[Term]
id: CCO:B0000008
name: CDC37_YEAST
def: "Hsp90 co-chaperone Cdc37" [UniProtKB:P06101]
synonym: "Cell division control protein 37" EXACT [UniProtKB:P06101]
synonym: "Hsp90 chaperone protein kinase-targeting subunit" EXACT [UniProtKB:P06101]
xref: EMBL:CAA27836.1
xref: EMBL:CAA87799.1
xref: UniProtKB:P06101
xref: UniProtKB:Q04132
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000288 ! CDC37_yeast
relationship: participates_in CCO:I0002348 ! ga-62 physical interaction
relationship: participates_in CCO:I0003060 ! atp3-cdc37 physical interaction
relationship: participates_in CCO:I0004977 ! ho-217 physical interaction
relationship: participates_in CCO:I0005309 ! hsp82-cdc37 physical interaction
relationship: participates_in CCO:I0005311 ! hsp82-cdc37-1 physical interaction
relationship: participates_in CCO:I0005470 ! atp3-3 physical interaction
relationship: participates_in CCO:I0005589 ! asc1-19 physical interaction
relationship: participates_in CCO:I0005683 ! hsc82-cdc37 physical interaction
relationship: participates_in CCO:I0005691 ! cdc37-hsp82 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: participates_in CCO:P0000112 ! spindle pole body duplication in nuclear envelope
relationship: participates_in CCO:P0000346 ! regulation of cell cycle
relationship: transforms_into CCO:B0006791 ! CDC37_YEAST-Phosphoserine14
relationship: transforms_into CCO:B0006792 ! CDC37_YEAST-Phosphoserine17
relationship: transforms_into CCO:B0006793 ! CDC37_YEAST-Phosphoserine367

[Term]
id: CCO:B0000010
name: SC160_YEAST
def: "Protein SCP160" [UniProtKB:P06105]
synonym: "Protein HX" EXACT [UniProtKB:P06105]
xref: EMBL:CAA28383.1
xref: EMBL:CAA46597.1
xref: EMBL:CAA58490.1
xref: EMBL:CAA61316.1
xref: EMBL:CAA89371.1
xref: EMBL:CAA89373.1
xref: UniProtKB:P06105
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002040 ! SCP160_yeast
relationship: participates_in CCO:I0002168 ! gpa1-scp160 physical interaction
relationship: participates_in CCO:I0002488 ! ga-374 physical interaction
relationship: participates_in CCO:I0002517 ! ga-433 physical interaction
relationship: participates_in CCO:I0002566 ! ga-588 physical interaction
relationship: participates_in CCO:I0002628 ! yhm4-asc1 physical interaction
relationship: participates_in CCO:I0003254 ! bfr1-asc1 physical interaction
relationship: participates_in CCO:I0003336 ! scp160-asc1 physical interaction
relationship: participates_in CCO:I0003415 ! gcr3-air2 physical interaction
relationship: participates_in CCO:I0003583 ! zuo1-asc1 physical interaction
relationship: participates_in CCO:I0004988 ! ho-238 physical interaction
relationship: participates_in CCO:I0005022 ! ho-305 physical interaction
relationship: participates_in CCO:I0005179 ! ho-591 physical interaction
relationship: participates_in CCO:I0005384 ! aar2-61 physical interaction
relationship: participates_in CCO:I0005408 ! ade5,7-40 physical interaction
relationship: participates_in CCO:I0005433 ! air2-29 physical interaction
relationship: participates_in CCO:I0005491 ! bur2-10 physical interaction
relationship: participates_in CCO:I0005503 ! asc1-17 physical interaction
relationship: participates_in CCO:I0005543 ! bem2-15 physical interaction
relationship: participates_in CCO:I0005589 ! asc1-19 physical interaction
relationship: participates_in CCO:I0005590 ! asc1-10 physical interaction
relationship: participates_in CCO:I0005666 ! scp160-ykl20w-1 physical interaction
relationship: participates_in CCO:P0000238 ! telomere clustering
relationship: transforms_into CCO:B0009065 ! SC160_YEAST-Phosphothreonine50
relationship: transforms_into CCO:B0009066 ! SC160_YEAST-Phosphoserine54
relationship: transforms_into CCO:B0009067 ! SC160_YEAST-Phosphoserine85
relationship: transforms_into CCO:B0009068 ! SC160_YEAST-Phosphoserine89
relationship: transforms_into CCO:B0009069 ! SC160_YEAST-Phosphoserine1112
relationship: transforms_into CCO:B0009070 ! SC160_YEAST-Phosphothreonine1120

[Term]
id: CCO:B0000011
name: PIS_YEAST
def: "CDP-diacylglycerol--inositol 3-phosphatidyltransferase" [UniProtKB:P06197]
synonym: "EC 2.7.8.11" EXACT [UniProtKB:P06197]
synonym: "Phosphatidylinositol synthase" EXACT [UniProtKB:P06197]
synonym: "PI synthase" EXACT [UniProtKB:P06197]
synonym: "PtdIns synthase" EXACT [UniProtKB:P06197]
xref: EMBL:AAA34876.1
xref: EMBL:AAB68083.1
xref: UniProtKB:P06197
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0001491 ! PIS1_yeast
relationship: located_in CCO:C0000325 ! mitochondrion
relationship: located_in CCO:C0000327 ! mitochondrial outer membrane
relationship: located_in CCO:C0000364 ! endoplasmic reticulum
relationship: located_in CCO:C0000373 ! microsome
relationship: located_in CCO:C0000766 ! membrane
relationship: located_in CCO:C0000767 ! integral to membrane
relationship: participates_in CCO:I0000964 ! ubc7-pis1 physical interaction
relationship: participates_in CCO:I0001173 ! gcs1-pis1 physical interaction
relationship: participates_in CCO:I0002039 ! pis1-erg6 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle

[Term]
id: CCO:B0000012
name: KIN28_YEAST
def: "Serine/threonine-protein kinase KIN28" [UniProtKB:P06242]
synonym: "EC 2.7.11.23" EXACT [UniProtKB:P06242]
xref: EMBL:CAA28019.1
xref: EMBL:CAA64904.1
xref: EMBL:CAA98675.1
xref: UniProtKB:P06242
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000989 ! KIN28_yeast
relationship: participates_in CCO:I0001112 ! kin28-ygl134w physical interaction
relationship: participates_in CCO:I0001982 ! bud7-kin28 physical interaction
relationship: participates_in CCO:I0002340 ! ga-54 physical interaction
relationship: participates_in CCO:I0002851 ! ccl1-dcs2 physical interaction
relationship: participates_in CCO:I0005056 ! ho-367 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: transforms_into CCO:B0007846 ! KIN28_YEAST-Phosphothreonine162

[Term]
id: CCO:B0000013
name: CDC7_YEAST
def: "Cell division control protein 7" [UniProtKB:P06243]
synonym: "EC 2.7.11.1" EXACT [UniProtKB:P06243]
xref: EMBL:AAA34485.1
xref: EMBL:CAA32369.1
xref: EMBL:CAA32370.1
xref: EMBL:CAA33420.1
xref: EMBL:CAA88342.1
xref: EMBL:CAA98574.1
xref: UniProtKB:P06243
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000301 ! CDC7_yeast
relationship: located_in CCO:C0000252 ! nucleus
relationship: located_in CCO:C0001246 ! Dbf4-dependent protein kinase complex
relationship: participates_in CCO:I0004403 ! cdc53-cdc7 physical interaction
relationship: participates_in CCO:I0004409 ! cdc7-arg3 physical interaction
relationship: participates_in CCO:I0004410 ! cdc7-dhh1 physical interaction
relationship: participates_in CCO:I0004411 ! cdc7-ptm1 physical interaction
relationship: participates_in CCO:I0004412 ! cdc7-tel2 physical interaction
relationship: participates_in CCO:I0004413 ! cdc7-ycr022c physical interaction
relationship: participates_in CCO:I0004414 ! cdc7-ycr050c physical interaction
relationship: participates_in CCO:I0004415 ! cdc7-yel023c physical interaction
relationship: participates_in CCO:I0004416 ! cdc7-yfr057w physical interaction
relationship: participates_in CCO:I0004417 ! cdc7-ynr048w physical interaction
relationship: participates_in CCO:I0004418 ! cdc7-yor006c physical interaction
relationship: participates_in CCO:I0005196 ! ho-629 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: participates_in CCO:P0000081 ! mitosis
relationship: participates_in CCO:P0000117 ! meiosis

[Term]
id: CCO:B0000014
name: KAPA_YEAST
def: "cAMP-dependent protein kinase type 1" [UniProtKB:P06244]
synonym: "CDC25-suppressing protein kinase" EXACT [UniProtKB:P06244]
synonym: "EC 2.7.11.11" EXACT [UniProtKB:P06244]
synonym: "PK-25" EXACT [UniProtKB:P06244]
synonym: "PKA 1" EXACT [UniProtKB:P06244]
xref: EMBL:AAA34877.1
xref: EMBL:AAA35088.1
xref: EMBL:AAA35164.1
xref: EMBL:AAX83942.1
xref: EMBL:CAA89459.1
xref: UniProtKB:P06244
xref: UniProtKB:P11595
xref: UniProtKB:Q2VQW1
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000962 ! TPK1_yeast
relationship: participates_in CCO:I0001527 ! tpk1-reg1 physical interaction
relationship: participates_in CCO:I0002873 ! tpk1-bcy1 physical interaction
relationship: participates_in CCO:I0004864 ! ho-23 physical interaction
relationship: participates_in CCO:I0005030 ! ho-319 physical interaction
relationship: participates_in CCO:I0005035 ! ho-329 physical interaction
relationship: participates_in CCO:I0005138 ! ho-514 physical interaction
relationship: participates_in CCO:I0005198 ! ho-631 physical interaction
relationship: participates_in CCO:I0005234 ! ho-716 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: transforms_into CCO:B0007764 ! KAPA_YEAST-Phosphothreonine241

[Term]
id: CCO:B0000015
name: CDC31_YEAST
def: "Cell division control protein 31" [UniProtKB:P06704]
synonym: "Nuclear pore protein CDC31" EXACT [UniProtKB:P06704]
synonym: "Nucleoporin CDC31" EXACT [UniProtKB:P06704]
xref: EMBL:AAA66893.1
xref: EMBL:AAS56760.1
xref: EMBL:CAA52609.1
xref: EMBL:CAA99479.1
xref: UniProtKB:P06704
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000287 ! CDC31_yeast
relationship: located_in CCO:C0000252 ! nucleus
relationship: located_in CCO:C0000260 ! nuclear pore
relationship: located_in CCO:C0000393 ! half bridge of spindle pole body
relationship: participates_in CCO:I0000694 ! hsh49-cdc31 physical interaction
relationship: participates_in CCO:I0001951 ! cdc31-kar1 physical interaction
relationship: participates_in CCO:I0004311 ! nup60-nup170 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: participates_in CCO:P0000081 ! mitosis
relationship: participates_in CCO:P0000112 ! spindle pole body duplication in nuclear envelope

[Term]
id: CCO:B0000016
name: RAD1_YEAST
def: "DNA repair protein RAD1" [UniProtKB:P06777]
xref: EMBL:AAA34929.1
xref: EMBL:AAA34934.1
xref: EMBL:AAB68165.1
xref: UniProtKB:P06777
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0001642 ! RAD1_yeast
relationship: located_in CCO:C0000004 ! nucleotide-excision repair factor 1 complex
relationship: located_in CCO:C0000252 ! nucleus
relationship: participates_in CCO:I0001997 ! rad1-slx4 physical interaction
relationship: participates_in CCO:I0002236 ! rad1-cca1 physical interaction
relationship: participates_in CCO:I0002237 ! rad1-guf1 physical interaction
relationship: participates_in CCO:I0002238 ! rad1-hrd3 physical interaction
relationship: participates_in CCO:I0002239 ! rad1-lcb4 physical interaction
relationship: participates_in CCO:I0002240 ! rad1-orc1 physical interaction
relationship: participates_in CCO:I0002241 ! rad1-sfh1 physical interaction
relationship: participates_in CCO:I0002242 ! rad1-ydr334w physical interaction
relationship: participates_in CCO:I0002243 ! rad1-ybl089w physical interaction
relationship: participates_in CCO:I0002244 ! rad1-swa2 physical interaction
relationship: participates_in CCO:I0002245 ! rad1-yer066w physical interaction
relationship: participates_in CCO:I0002246 ! rad1-ygl050w physical interaction
relationship: participates_in CCO:I0002247 ! rad1-yhr112c physical interaction
relationship: participates_in CCO:I0002248 ! rad1-ykl179c physical interaction
relationship: participates_in CCO:I0002249 ! rad1-yor051c physical interaction
relationship: participates_in CCO:I0002540 ! ga-496 physical interaction
relationship: participates_in CCO:I0003225 ! yac7-adh1 physical interaction
relationship: participates_in CCO:I0004873 ! ho-40 physical interaction
relationship: participates_in CCO:I0004911 ! ho-104 physical interaction
relationship: participates_in CCO:I0004961 ! ho-195 physical interaction
relationship: participates_in CCO:I0004986 ! ho-236 physical interaction
relationship: participates_in CCO:I0005054 ! ho-364 physical interaction
relationship: participates_in CCO:I0005069 ! ho-402 physical interaction
relationship: participates_in CCO:I0005112 ! ho-468 physical interaction
relationship: participates_in CCO:I0005140 ! ho-522 physical interaction
relationship: participates_in CCO:P0000048 ! meiotic mismatch repair
relationship: transforms_into CCO:B0008653 ! RAD1_YEAST-Phosphoserine1071
relationship: transforms_into CCO:B0008654 ! RAD1_YEAST-Phosphothreonine1072

[Term]
id: CCO:B0000017
name: RAD52_YEAST
def: "DNA repair and recombination protein RAD52" [UniProtKB:P06778]
xref: EMBL:AAA50352.1
xref: EMBL:AAT93163.1
xref: EMBL:CAA86623.1
xref: UniProtKB:P06778
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0001653 ! RAD52_yeast
relationship: located_in CCO:C0000040 ! nuclear chromosome
relationship: located_in CCO:C0000252 ! nucleus
relationship: participates_in CCO:I0000585 ! hmt1-rad52 physical interaction
relationship: participates_in CCO:I0002423 ! ga-234 physical interaction
relationship: participates_in CCO:I0002463 ! ga-320 physical interaction
relationship: participates_in CCO:I0002468 ! ga-329 physical interaction
relationship: participates_in CCO:I0002817 ! rad52-mpg1 physical interaction
relationship: participates_in CCO:I0003287 ! msh6-lcd1 physical interaction
relationship: participates_in CCO:I0003357 ! rfa1-dna2 physical interaction
relationship: participates_in CCO:I0003482 ! rad51-aro1 physical interaction
relationship: participates_in CCO:I0003572 ! rad52-rfa1 physical interaction
relationship: participates_in CCO:I0003594 ! gpi17-ktr2 physical interaction
relationship: participates_in CCO:I0005048 ! ho-354 physical interaction
relationship: participates_in CCO:I0005165 ! ho-564 physical interaction
relationship: participates_in CCO:I0005401 ! dna2-17 physical interaction
relationship: participates_in CCO:I0005434 ! lcd1-10 physical interaction
relationship: participates_in CCO:I0005685 ! hsc82-rad52 physical interaction
relationship: participates_in CCO:P0000045 ! meiotic DNA recombinase assembly

[Term]
id: CCO:B0000018
name: TOP2_YEAST
def: "DNA topoisomerase 2" [UniProtKB:P06786]
synonym: "DNA topoisomerase II" EXACT [UniProtKB:P06786]
synonym: "EC 5.99.1.3" EXACT [UniProtKB:P06786]
xref: EMBL:AAB36610.1
xref: EMBL:AAM00518.1
xref: EMBL:AAM00530.1
xref: EMBL:AAM00536.1
xref: EMBL:CAA61422.1
xref: EMBL:CAA95964.1
xref: UniProtKB:P06786
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002440 ! TOP2_yeast
relationship: participates_in CCO:I0001864 ! top2-smt3 physical interaction
relationship: participates_in CCO:I0001865 ! top2-faa4 physical interaction
relationship: participates_in CCO:I0001866 ! top2-tir2 physical interaction
relationship: participates_in CCO:I0002357 ! ga-72 physical interaction
relationship: participates_in CCO:I0002530 ! ga-456 physical interaction
relationship: participates_in CCO:I0002603 ! top2-rfc5 physical interaction
relationship: participates_in CCO:I0002630 ! yju7-act1 physical interaction
relationship: participates_in CCO:I0002667 ! mft1-adh1 physical interaction
relationship: participates_in CCO:I0002707 ! tsc13-bni1 physical interaction
relationship: participates_in CCO:I0002730 ! ubp4-ded1 physical interaction
relationship: participates_in CCO:I0002783 ! omp2-adh1 physical interaction
relationship: participates_in CCO:I0003092 ! q3e7y5-gls1 physical interaction
relationship: participates_in CCO:I0003419 ! nth1-bmh1 physical interaction
relationship: participates_in CCO:I0003436 ! cch1-cdc68 physical interaction
relationship: participates_in CCO:I0003451 ! ceg1-bem2 physical interaction
relationship: participates_in CCO:I0003629 ! yb09-gcd1 physical interaction
relationship: participates_in CCO:I0004915 ! ho-110 physical interaction
relationship: participates_in CCO:I0004968 ! ho-205 physical interaction
relationship: participates_in CCO:I0005211 ! ho-659 physical interaction
relationship: participates_in CCO:I0005440 ! aro1-21 physical interaction
relationship: participates_in CCO:I0005462 ! eno2-7 physical interaction
relationship: participates_in CCO:I0005469 ! aap1-16 physical interaction
relationship: participates_in CCO:I0005486 ! atp2-16 physical interaction
relationship: participates_in CCO:I0005549 ! ala1-27 physical interaction
relationship: participates_in CCO:I0005607 ! hir2-8 physical interaction
relationship: participates_in CCO:I0005627 ! bmh1-10 physical interaction
relationship: participates_in CCO:P0000122 ! meiotic recombination
relationship: transforms_into CCO:B0009657 ! TOP2_YEAST-Phosphothreonine1086
relationship: transforms_into CCO:B0009658 ! TOP2_YEAST-Phosphoserine1087
relationship: transforms_into CCO:B0009659 ! TOP2_YEAST-Phosphothreonine1250
relationship: transforms_into CCO:B0009660 ! TOP2_YEAST-Phosphothreonine1258
relationship: transforms_into CCO:B0009661 ! TOP2_YEAST-Phosphoserine1266
relationship: transforms_into CCO:B0009662 ! TOP2_YEAST-Phosphoserine1269
relationship: transforms_into CCO:B0009663 ! TOP2_YEAST-Phosphoserine1272
relationship: transforms_into CCO:B0009664 ! TOP2_YEAST-Phosphothreonine1306
relationship: transforms_into CCO:B0009665 ! TOP2_YEAST-Phosphothreonine1309
relationship: transforms_into CCO:B0009666 ! TOP2_YEAST-Phosphoserine1310
relationship: transforms_into CCO:B0009667 ! TOP2_YEAST-Phosphothreonine1314
relationship: transforms_into CCO:B0009668 ! TOP2_YEAST-Phosphoserine1353
relationship: transforms_into CCO:B0009669 ! TOP2_YEAST-Phosphoserine1356
relationship: transforms_into CCO:B0009670 ! TOP2_YEAST-Phosphoserine1408
relationship: transforms_into CCO:B0009671 ! TOP2_YEAST-Phosphoserine1423

[Term]
id: CCO:B0000019
name: CALM_YEAST
def: "Calmodulin" [UniProtKB:P06787]
synonym: "CaM" EXACT [UniProtKB:P06787]
xref: EMBL:AAA34504.1
xref: EMBL:AAC68888.1
xref: EMBL:AAS56510.1
xref: EMBL:CAA55612.1
xref: EMBL:CAA85064.1
xref: UniProtKB:P06787
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000244 ! CMD1_yeast
relationship: located_in CCO:C0000016 ! incipient cellular bud site
relationship: located_in CCO:C0000391 ! central plaque of spindle pole body
relationship: located_in CCO:C0000486 ! cellular bud tip
relationship: located_in CCO:C0000487 ! cellular bud neck
relationship: located_in CCO:C0001770 ! mating projection tip
relationship: participates_in CCO:I0002132 ! cmd1-yml094c_a physical interaction
relationship: participates_in CCO:I0002133 ! cmd1-ymr111c physical interaction
relationship: participates_in CCO:I0002427 ! ga-244 physical interaction
relationship: participates_in CCO:I0002572 ! mcm5-act1 physical interaction
relationship: participates_in CCO:I0002895 ! myo2-cmd1 physical interaction
relationship: participates_in CCO:I0002932 ! cmk1-aac2 physical interaction
relationship: participates_in CCO:I0002974 ! cna2-cmd1 physical interaction
relationship: participates_in CCO:I0003080 ! vps13-cmd1 physical interaction
relationship: participates_in CCO:I0003125 ! cna1-cmd1 physical interaction
relationship: participates_in CCO:I0003208 ! vps13-cmd1-1 physical interaction
relationship: participates_in CCO:I0003263 ! myo5-act1 physical interaction
relationship: participates_in CCO:I0003484 ! pwp1-act1-1 physical interaction
relationship: participates_in CCO:I0003520 ! myo3-cmd1 physical interaction
relationship: participates_in CCO:I0003805 ! rsp5-cmd1 direct interaction
relationship: participates_in CCO:I0003809 ! yfb0-cmd1 direct interaction
relationship: participates_in CCO:I0003813 ! set2-cmd1 direct interaction
relationship: participates_in CCO:I0003815 ! ess1-cmd1 direct interaction
relationship: participates_in CCO:I0003818 ! prp40-cmd1 direct interaction
relationship: participates_in CCO:I0003821 ! q06525-cmd1 direct interaction
relationship: participates_in CCO:I0004866 ! ho-25 physical interaction
relationship: participates_in CCO:I0004899 ! ho-80 physical interaction
relationship: participates_in CCO:I0004970 ! ho-207 physical interaction
relationship: participates_in CCO:I0005201 ! ho-636 physical interaction
relationship: participates_in CCO:I0005221 ! ho-688 physical interaction
relationship: participates_in CCO:I0005418 ! arsa-11 physical interaction
relationship: participates_in CCO:I0005421 ! act1-27 physical interaction
relationship: participates_in CCO:I0005505 ! cdc47-7 physical interaction
relationship: participates_in CCO:I0005598 ! aac2-14 physical interaction
relationship: participates_in CCO:I0005647 ! act1-19-1 physical interaction
relationship: participates_in CCO:P0000302 ! spindle pole body organization and biogenesis
relationship: transforms_into CCO:B0006731 ! CALM_YEAST-Phosphoserine112

[Term]
id: CCO:B0000020
name: RAD10_YEAST
def: "DNA repair protein RAD10" [UniProtKB:P06838]
xref: EMBL:CAA26433.1
xref: EMBL:CAA28856.1
xref: EMBL:CAA86642.1
xref: UniProtKB:P06838
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0001638 ! RAD10_yeast
relationship: located_in CCO:C0000004 ! nucleotide-excision repair factor 1 complex
relationship: located_in CCO:C0000252 ! nucleus
relationship: participates_in CCO:I0001801 ! rad10-spt4 physical interaction
relationship: participates_in CCO:I0002540 ! ga-496 physical interaction
relationship: participates_in CCO:I0003225 ! yac7-adh1 physical interaction
relationship: participates_in CCO:I0004540 ! rad10-gcd1 physical interaction
relationship: participates_in CCO:I0004541 ! rad10-ycr086w physical interaction
relationship: participates_in CCO:I0004986 ! ho-236 physical interaction
relationship: participates_in CCO:I0005069 ! ho-402 physical interaction
relationship: participates_in CCO:I0005112 ! ho-468 physical interaction
relationship: participates_in CCO:P0000048 ! meiotic mismatch repair

[Term]
id: CCO:B0000021
name: IF4E_YEAST
def: "Eukaryotic translation initiation factor 4E" [UniProtKB:P07260]
synonym: "eIF-4E" EXACT [UniProtKB:P07260]
synonym: "eIF-4F 25 kDa subunit" EXACT [UniProtKB:P07260]
synonym: "eIF4E" EXACT [UniProtKB:P07260]
synonym: "mRNA cap-binding protein" EXACT [UniProtKB:P07260]
xref: EMBL:AAA34480.1
xref: EMBL:AAA34587.1
xref: EMBL:AAA34588.1
xref: EMBL:AAT92955.1
xref: EMBL:CAA58854.1
xref: EMBL:CAA99160.1
xref: UniProtKB:P07260
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000897 ! TIF45_yeast
relationship: participates_in CCO:I0001680 ! mec3-tif45 physical interaction
relationship: participates_in CCO:I0001919 ! tif45-caf20 physical interaction
relationship: participates_in CCO:I0002322 ! ga-205 physical interaction
relationship: participates_in CCO:I0002346 ! ga-60 physical interaction
relationship: participates_in CCO:I0002408 ! ga-208 physical interaction
relationship: participates_in CCO:I0002528 ! ga-451 physical interaction
relationship: participates_in CCO:I0002542 ! ga-502 physical interaction
relationship: participates_in CCO:I0002578 ! smb1-aar2 physical interaction
relationship: participates_in CCO:I0002584 ! chs5-asc1 physical interaction
relationship: participates_in CCO:I0002598 ! tif4632-hhf1 physical interaction
relationship: participates_in CCO:I0002634 ! imd3-imd2 physical interaction
relationship: participates_in CCO:I0002661 ! luc7-brr2 physical interaction
relationship: participates_in CCO:I0002797 ! tif4631-asc1 physical interaction
relationship: participates_in CCO:I0002846 ! tif45-gbp2 physical interaction
relationship: participates_in CCO:I0002923 ! imd4-imd2 physical interaction
relationship: participates_in CCO:I0003063 ! ybd2-cbf5 physical interaction
relationship: participates_in CCO:I0003109 ! ssbr1-asc1 physical interaction
relationship: participates_in CCO:I0003194 ! fur4-act1 physical interaction
relationship: participates_in CCO:I0003219 ! yku4-ssa2 physical interaction
relationship: participates_in CCO:I0003359 ! caf20-ssa2 physical interaction
relationship: participates_in CCO:I0003504 ! cdc27-pab1 physical interaction
relationship: participates_in CCO:I0003614 ! lsm7-brr2 physical interaction
relationship: participates_in CCO:I0003645 ! ssbr1-adh1 physical interaction
relationship: participates_in CCO:I0003780 ! tif4631-tif45-3 physical interaction
relationship: participates_in CCO:I0003902 ! if43yeast-if4eyeast physical interaction
relationship: participates_in CCO:I0003903 ! if4yeast-if43eyeast physical interaction
relationship: participates_in CCO:I0003907 ! gcn5-ada2-1 physical interaction
relationship: participates_in CCO:I0003977 ! tif4631-tif45-5 direct interaction
relationship: participates_in CCO:I0004308 ! f41yeast -if4eyeast physical interaction
relationship: participates_in CCO:I0004309 ! if41yeast -if4eyeast physical interaction
relationship: participates_in CCO:I0004397 ! caf20-tif45 physical interaction
relationship: participates_in CCO:I0004400 ! tif45-caf20-1 physical interaction
relationship: participates_in CCO:I0004797 ! trx1-ahp1-2 physical interaction
relationship: participates_in CCO:I0004798 ! trx2-ahp1-2 physical interaction
relationship: participates_in CCO:I0004820 ! tif4631-tif45-2 direct interaction
relationship: participates_in CCO:I0004860 ! ho-18 physical interaction
relationship: participates_in CCO:I0004865 ! ho-24 physical interaction
relationship: participates_in CCO:I0004869 ! ho-31 physical interaction
relationship: participates_in CCO:I0004918 ! ho-119 physical interaction
relationship: participates_in CCO:I0004921 ! ho-125 physical interaction
relationship: participates_in CCO:I0004988 ! ho-238 physical interaction
relationship: participates_in CCO:I0005009 ! ho-282 physical interaction
relationship: participates_in CCO:I0005029 ! ho-317 physical interaction
relationship: participates_in CCO:I0005043 ! ho-343 physical interaction
relationship: participates_in CCO:I0005057 ! ho-368 physical interaction
relationship: participates_in CCO:I0005113 ! ho-469 physical interaction
relationship: participates_in CCO:I0005120 ! ho-480 physical interaction
relationship: participates_in CCO:I0005125 ! ho-488 physical interaction
relationship: participates_in CCO:I0005135 ! ho-506 physical interaction
relationship: participates_in CCO:I0005141 ! ho-523 physical interaction
relationship: participates_in CCO:I0005149 ! ho-538 physical interaction
relationship: participates_in CCO:I0005161 ! ho-557 physical interaction
relationship: participates_in CCO:I0005164 ! ho-563 physical interaction
relationship: participates_in CCO:I0005166 ! ho-565 physical interaction
relationship: participates_in CCO:I0005167 ! ho-567 physical interaction
relationship: participates_in CCO:I0005198 ! ho-631 physical interaction
relationship: participates_in CCO:I0005228 ! ho-705 physical interaction
relationship: participates_in CCO:I0005232 ! ho-712 physical interaction
relationship: participates_in CCO:I0005329 ! tif4631-tif45-1 physical interaction
relationship: participates_in CCO:I0005330 ! tif4631-tif45-4 physical interaction
relationship: participates_in CCO:I0005409 ! brr2-34 physical interaction
relationship: participates_in CCO:I0005433 ! air2-29 physical interaction
relationship: participates_in CCO:I0005436 ! aar2-39 physical interaction
relationship: participates_in CCO:I0005460 ! bob1-11 physical interaction
relationship: participates_in CCO:I0005519 ! imd2-7 physical interaction
relationship: participates_in CCO:I0005530 ! cbf5-23 physical interaction
relationship: participates_in CCO:I0005559 ! bur2-23 physical interaction
relationship: participates_in CCO:I0005609 ! atg26-45 physical interaction
relationship: participates_in CCO:I0005616 ! aar2-53 physical interaction
relationship: participates_in CCO:I0005621 ! imd4-11 physical interaction
relationship: participates_in CCO:I0005638 ! bre5-10 physical interaction
relationship: participates_in CCO:P0000346 ! regulation of cell cycle
relationship: transforms_into CCO:B0007651 ! IF4E_YEAST-Phosphoserine2
relationship: transforms_into CCO:B0007652 ! IF4E_YEAST-Phosphoserine15
relationship: transforms_into CCO:B0007653 ! IF4E_YEAST-Phosphothreonine22
relationship: transforms_into CCO:B0007654 ! IF4E_YEAST-Phosphoserine28
relationship: transforms_into CCO:B0007655 ! IF4E_YEAST-Phosphoserine30

[Term]
id: CCO:B0000023
name: CDC4_YEAST
def: "Cell division control protein 4" [UniProtKB:P07834]
synonym: "E3 ubiquitin ligase complex SCF subunit CDC4" EXACT [UniProtKB:P07834]
synonym: "F-box protein CDC4" EXACT [UniProtKB:P07834]
xref: EMBL:BAA09229.1
xref: EMBL:CAA29113.1
xref: EMBL:CAA86341.1
xref: UniProtKB:P07834
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000294 ! CDC4_yeast
relationship: located_in CCO:C0000252 ! nucleus
relationship: located_in CCO:C0000785 ! nuclear matrix
relationship: located_in CCO:C0000850 ! SCF ubiquitin ligase complex
relationship: located_in CCO:C0001741 ! nuclear SCF ubiquitin ligase complex
relationship: participates_in CCO:I0000507 ! cwc2-cdc4 physical interaction
relationship: participates_in CCO:I0003770 ! cbf3d-cdc4-2 physical interaction
relationship: participates_in CCO:I0003972 ! cdc53-cdc4 physical interaction
relationship: participates_in CCO:I0003974 ! cdc53-cdc4-1 physical interaction
relationship: participates_in CCO:I0004344 ! cdc53-cbf3d-3 physical interaction
relationship: participates_in CCO:I0004345 ! cdc53-cbf3d-4 physical interaction
relationship: participates_in CCO:I0004348 ! cdc4-cdc53 physical interaction
relationship: participates_in CCO:I0004349 ! cdc53-cbf3d-5 physical interaction
relationship: participates_in CCO:I0004353 ! cdc53-cbf3d-6 physical interaction
relationship: participates_in CCO:I0004356 ! cbf3d-cdc4-1 physical interaction
relationship: participates_in CCO:I0004573 ! cbf3d-cdc4 physical interaction
relationship: participates_in CCO:I0004817 ! cdc4-cdc6 physical interaction
relationship: participates_in CCO:I0004984 ! ho-233 physical interaction
relationship: participates_in CCO:I0005038 ! ho-336 physical interaction
relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle
relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: participates_in CCO:P0000081 ! mitosis
relationship: participates_in CCO:P0000117 ! meiosis

[Term]
id: CCO:B0000024
name: LTE1_YEAST
def: "Guanine nucleotide exchange factor LTE1" [UniProtKB:P07866]
synonym: "Low temperature essential protein 1" EXACT [UniProtKB:P07866]
xref: EMBL:AAA34746.1
xref: EMBL:AAA34751.1
xref: EMBL:AAA50468.1
xref: EMBL:AAC05008.1
xref: EMBL:BAA04820.1
xref: UniProtKB:P07866
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0001059 ! LTE1_yeast
relationship: located_in CCO:C0000242 ! intracellular
relationship: located_in CCO:C0000324 ! cytoplasm
relationship: located_in CCO:C0000485 ! cellular bud
relationship: participates_in CCO:I0000759 ! zds2-lte1 physical interaction
relationship: participates_in CCO:I0000871 ! met30-lte1 physical interaction
relationship: participates_in CCO:I0002407 ! ga-207 physical interaction
relationship: participates_in CCO:I0002531 ! ga-458 physical interaction
relationship: participates_in CCO:I0002736 ! lte1-kel1 physical interaction
relationship: participates_in CCO:I0002918 ! kel1-bem2 physical interaction
relationship: participates_in CCO:I0003271 ! tpd3-cdc55-1 physical interaction
relationship: participates_in CCO:I0003918 ! lte1-ade4 physical interaction
relationship: participates_in CCO:I0005501 ! bem2-3 physical interaction
relationship: participates_in CCO:I0005532 ! cdc55-19 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: participates_in CCO:P0000081 ! mitosis
relationship: participates_in CCO:P0000107 ! regulation of exit from mitosis
relationship: participates_in CCO:P0000191 ! mitotic cell cycle spindle orientation checkpoint

[Term]
id: CCO:B0000025
name: SWI5_YEAST
def: "Transcriptional factor SWI5" [UniProtKB:P08153]
xref: EMBL:CAA30040.1
xref: EMBL:CAA90369.1
xref: UniProtKB:P08153
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002319 ! SWI5_yeast
relationship: located_in CCO:C0000242 ! intracellular
relationship: located_in CCO:C0000252 ! nucleus
relationship: located_in CCO:C0000324 ! cytoplasm
relationship: participates_in CCO:I0000834 ! ynm4-swi5 physical interaction
relationship: participates_in CCO:I0002304 ! swi5-mei5 physical interaction
relationship: participates_in CCO:I0002305 ! swi5-ycr087w physical interaction
relationship: participates_in CCO:I0004296 ! swi5-yg2k physical interaction
relationship: participates_in CCO:I0004502 ! msn5-swi5 physical interaction
relationship: participates_in CCO:I0004520 ! pcl2-swi5 physical interaction
relationship: participates_in CCO:I0005067 ! ho-391 physical interaction
relationship: participates_in CCO:P0000024 ! G1-specific transcription in mitotic cell cycle
relationship: transforms_into CCO:B0009555 ! SWI5_YEAST-Phosphoserine278
relationship: transforms_into CCO:B0009556 ! SWI5_YEAST-Phosphoserine492
relationship: transforms_into CCO:B0009557 ! SWI5_YEAST-Phosphoserine505
relationship: transforms_into CCO:B0009558 ! SWI5_YEAST-Phosphoserine522
relationship: transforms_into CCO:B0009559 ! SWI5_YEAST-Phosphoserine646
relationship: transforms_into CCO:B0009560 ! SWI5_YEAST-Phosphoserine664

[Term]
id: CCO:B0000026
name: SPS1_YEAST
def: "Sporulation-specific protein 1" [UniProtKB:P08458]
synonym: "EC 2.7.11.1" EXACT [UniProtKB:P08458]
xref: EMBL:AAA35079.1
xref: EMBL:AAA64833.1
xref: EMBL:AAB64963.1
xref: UniProtKB:P08458
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002231 ! SPS1_yeast
relationship: located_in CCO:C0000247 ! prospore membrane
relationship: located_in CCO:C0000252 ! nucleus
relationship: located_in CCO:C0000324 ! cytoplasm
relationship: participates_in CCO:I0004868 ! ho-29 physical interaction
relationship: participates_in CCO:I0004956 ! ho-182 physical interaction
relationship: participates_in CCO:P0000117 ! meiosis

[Term]
id: CCO:B0000027
name: SPS2_YEAST
def: "Sporulation-specific protein 2 precursor" [UniProtKB:P08459]
xref: EMBL:AAA35080.1
xref: EMBL:AAB64962.1
xref: UniProtKB:P08459
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002232 ! SPS2_yeast
relationship: located_in CCO:C0000444 ! plasma membrane
relationship: located_in CCO:C0000766 ! membrane
relationship: located_in CCO:C0001149 ! anchored to membrane
relationship: located_in CCO:C0002066 ! fungal-type cell wall
relationship: participates_in CCO:I0000825 ! ynm4-sps2 physical interaction
relationship: participates_in CCO:I0000947 ! ubc7-sps2 physical interaction
relationship: participates_in CCO:P0000117 ! meiosis

[Term]
id: CCO:B0000028
name: MYO1_YEAST
def: "Myosin-1" [UniProtKB:P08964]
synonym: "Type II myosin" EXACT [UniProtKB:P08964]
xref: EMBL:AAB68872.1
xref: EMBL:CAA29550.1
xref: EMBL:CAA37894.1
xref: UniProtKB:P08964
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0001242 ! MYO1_yeast
relationship: participates_in CCO:I0002329 ! ga-27 physical interaction
relationship: participates_in CCO:I0002426 ! ga-243 physical interaction
relationship: participates_in CCO:I0002521 ! ga-438 physical interaction
relationship: participates_in CCO:I0002572 ! mcm5-act1 physical interaction
relationship: participates_in CCO:I0002625 ! myo1-act1 physical interaction
relationship: participates_in CCO:I0002755 ! yfd4-myo1 physical interaction
relationship: participates_in CCO:I0002793 ! taf12-ada3 physical interaction
relationship: participates_in CCO:I0002794 ! ard1-asc1 physical interaction
relationship: participates_in CCO:I0003306 ! ym8x-aro1 physical interaction
relationship: participates_in CCO:I0003353 ! taf1-ada2 physical interaction
relationship: participates_in CCO:I0003484 ! pwp1-act1-1 physical interaction
relationship: participates_in CCO:I0003942 ! swc4-eaf3 physical interaction
relationship: participates_in CCO:I0005418 ! arsa-11 physical interaction
relationship: participates_in CCO:I0005421 ! act1-27 physical interaction
relationship: participates_in CCO:I0005577 ! med4-15 physical interaction
relationship: participates_in CCO:I0005583 ! act1-14 physical interaction
relationship: participates_in CCO:I0005635 ! hem13-19 physical interaction
relationship: participates_in CCO:I0005647 ! act1-19-1 physical interaction
relationship: participates_in CCO:P0000059 ! cytokinesis, contractile ring formation
relationship: participates_in CCO:P0000060 ! contractile ring contraction involved in cytokinesis
relationship: transforms_into CCO:B0008111 ! MYO1_YEAST-Phosphoserine1171
relationship: transforms_into CCO:B0008112 ! MYO1_YEAST-Phosphoserine1476
relationship: transforms_into CCO:B0008113 ! MYO1_YEAST-Phosphothreonine1477

[Term]
id: CCO:B0000029
name: CDC6_YEAST
def: "Cell division control protein 6" [UniProtKB:P09119]
xref: EMBL:AAA34483.1
xref: EMBL:AAA34484.1
xref: EMBL:AAA34488.1
xref: EMBL:CAA31510.1
xref: EMBL:CAA46392.1
xref: EMBL:CAA54766.1
xref: EMBL:CAA89490.1
xref: UniProtKB:P09119
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000299 ! CDC6_yeast
relationship: located_in CCO:C0000264 ! pre-replicative complex
relationship: located_in CCO:C0000444 ! plasma membrane
relationship: located_in CCO:C0000766 ! membrane
relationship: located_in CCO:C0001181 ! DNA replication preinitiation complex
relationship: participates_in CCO:I0002484 ! ga-365 physical interaction
relationship: participates_in CCO:I0002549 ! ga-532 physical interaction
relationship: participates_in CCO:I0002801 ! rpt1-cdc6 physical interaction
relationship: participates_in CCO:I0003161 ! sec39-adh1-1 physical interaction
relationship: participates_in CCO:I0003362 ! rmd7-adh1 physical interaction
relationship: participates_in CCO:I0003481 ! yd96-cdc6 physical interaction
relationship: participates_in CCO:I0003489 ! yfe4-cdc48 physical interaction
relationship: participates_in CCO:I0004753 ! yfj4-cdc6 direct interaction
relationship: participates_in CCO:I0004817 ! cdc4-cdc6 physical interaction
relationship: participates_in CCO:I0005441 ! cdc6-41 physical interaction
relationship: participates_in CCO:I0005465 ! adh1-12 physical interaction
relationship: participates_in CCO:I0005595 ! arsa-cdc6 physical interaction
relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle
relationship: participates_in CCO:P0000066 ! cell cycle

[Term]
id: CCO:B0000030
name: TBA1_YEAST
def: "Tubulin alpha-1 chain" [UniProtKB:P09733]
xref: EMBL:AAA35180.1
xref: EMBL:CAA86653.1
xref: UniProtKB:P09733
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002371 ! TUB1_yeast
relationship: located_in CCO:C0000386 ! spindle pole body
relationship: located_in CCO:C0000395 ! polar microtubule
relationship: located_in CCO:C0000396 ! kinetochore microtubule
relationship: located_in CCO:C0000434 ! microtubule
relationship: located_in CCO:C0000438 ! nuclear microtubule
relationship: located_in CCO:C0000439 ! cytoplasmic microtubule
relationship: located_in CCO:C0001750 ! protein complex
relationship: participates_in CCO:I0002572 ! mcm5-act1 physical interaction
relationship: participates_in CCO:I0002573 ! tfb3-mpg1 physical interaction
relationship: participates_in CCO:I0002579 ! gcn1-aac2 physical interaction
relationship: participates_in CCO:I0002581 ! sec16-adh1 physical interaction
relationship: participates_in CCO:I0002604 ! ym52-mcm5 physical interaction
relationship: participates_in CCO:I0002606 ! yht1-cka1 physical interaction
relationship: participates_in CCO:I0002608 ! yg5y-rpl4b physical interaction
relationship: participates_in CCO:I0002610 ! mpa43-act1 physical interaction
relationship: participates_in CCO:I0002618 ! fth1-adh1 physical interaction
relationship: participates_in CCO:I0002619 ! mae1-aro1 physical interaction
relationship: participates_in CCO:I0002629 ! mis1-asc1 physical interaction
relationship: participates_in CCO:I0002630 ! yju7-act1 physical interaction
relationship: participates_in CCO:I0002631 ! ymb8-atp2 physical interaction
relationship: participates_in CCO:I0002632 ! vap1-hsp42 physical interaction
relationship: participates_in CCO:I0002633 ! yjg2-ssa1 physical interaction
relationship: participates_in CCO:I0002641 ! chl12-brr2 physical interaction
relationship: participates_in CCO:I0002642 ! ost1-ero1 physical interaction
relationship: participates_in CCO:I0002643 ! wtm1-hsp60 physical interaction
relationship: participates_in CCO:I0002645 ! vid27-adh1 physical interaction
relationship: participates_in CCO:I0002648 ! zrc1-gcn1 physical interaction
relationship: participates_in CCO:I0002653 ! mrd1-cct4 physical interaction
relationship: participates_in CCO:I0002658 ! sks1-hsp42 physical interaction
relationship: participates_in CCO:I0002660 ! ape2-aco1 physical interaction
relationship: participates_in CCO:I0002662 ! ykg5-adh1 physical interaction
relationship: participates_in CCO:I0002664 ! rps0a-act1 physical interaction
relationship: participates_in CCO:I0002671 ! ole1-anp1 physical interaction
relationship: participates_in CCO:I0002675 ! hmg1-adh1 physical interaction
relationship: participates_in CCO:I0002681 ! mcm6-hhf1 physical interaction
relationship: participates_in CCO:I0002684 ! acs2-asc1 physical interaction
relationship: participates_in CCO:I0002685 ! yn53-atp2 physical interaction
relationship: participates_in CCO:I0002687 ! sec7-adh1 physical interaction
relationship: participates_in CCO:I0002690 ! vps1-ssa2 physical interaction
relationship: participates_in CCO:I0002691 ! ctp1-hsp60 physical interaction
relationship: participates_in CCO:I0002695 ! hmg2-adh1 physical interaction
relationship: participates_in CCO:I0002697 ! mir1-ecm29 physical interaction
relationship: participates_in CCO:I0002707 ! tsc13-bni1 physical interaction
relationship: participates_in CCO:I0002708 ! sec2-act1 physical interaction
relationship: participates_in CCO:I0002711 ! erd2-bni1 physical interaction
relationship: participates_in CCO:I0002712 ! aac3-rpl27a physical interaction
relationship: participates_in CCO:I0002713 ! ald5-hsp60 physical interaction
relationship: participates_in CCO:I0002717 ! hsp26-eft1 physical interaction
relationship: participates_in CCO:I0002725 ! q12029-adh1 physical interaction
relationship: participates_in CCO:I0002728 ! yhm2-adh1 physical interaction
relationship: participates_in CCO:I0002739 ! pmr1-anp1 physical interaction
relationship: participates_in CCO:I0002741 ! kap114-htb1 physical interaction
relationship: participates_in CCO:I0002744 ! phb1-mpg1 physical interaction
relationship: participates_in CCO:I0002746 ! pyk2-mpg1 physical interaction
relationship: participates_in CCO:I0002752 ! ies3-adh1 physical interaction
relationship: participates_in CCO:I0002754 ! not5-mpg1 physical interaction
relationship: participates_in CCO:I0002758 ! mcr1-atp2 physical interaction
relationship: participates_in CCO:I0002777 ! sur2-rpl10 physical interaction
relationship: participates_in CCO:I0002783 ! omp2-adh1 physical interaction
relationship: participates_in CCO:I0002791 ! smc3-cct8 physical interaction
relationship: participates_in CCO:I0002795 ! npr1-act1 physical interaction
relationship: participates_in CCO:I0002798 ! cdc28-asc1 physical interaction
relationship: participates_in CCO:I0002799 ! rfc4-chl12 physical interaction
relationship: participates_in CCO:I0002803 ! sec24-cys4 physical interaction
relationship: participates_in CCO:I0002806 ! chs2-act1 physical interaction
relationship: participates_in CCO:I0002808 ! ymf5-adh1 physical interaction
relationship: participates_in CCO:I0002813 ! sfb2-adh1 physical interaction
relationship: participates_in CCO:I0002814 ! lcb1-lcb2 physical interaction
relationship: participates_in CCO:I0002816 ! yij0-adh1-1 physical interaction
relationship: participates_in CCO:I0002818 ! cdc54-mpg1 physical interaction
relationship: participates_in CCO:I0002821 ! erg25-ade5,7 physical interaction
relationship: participates_in CCO:I0002822 ! rpl23a-bcp1 physical interaction
relationship: participates_in CCO:I0002824 ! ubp1-adh1 physical interaction
relationship: participates_in CCO:I0002833 ! lsm6-brr2 physical interaction
relationship: participates_in CCO:I0002841 ! dpm1-kar2 physical interaction
relationship: participates_in CCO:I0002844 ! rer2-rpl4b physical interaction
relationship: participates_in CCO:I0002845 ! ym44-atp2 physical interaction
relationship: participates_in CCO:I0002849 ! q12510-rfa1 physical interaction
relationship: participates_in CCO:I0002850 ! car1-cdc60 physical interaction
relationship: participates_in CCO:I0002858 ! yb64-rps0a physical interaction
relationship: participates_in CCO:I0002862 ! mdj1-ecm29 physical interaction
relationship: participates_in CCO:I0002870 ! rad3-asc1 physical interaction
relationship: participates_in CCO:I0002871 ! hch1-adh1 physical interaction
relationship: participates_in CCO:I0002872 ! rvs167-ecm29 physical interaction
relationship: participates_in CCO:I0002884 ! vph1-adh1 physical interaction
relationship: participates_in CCO:I0002888 ! cox13-gls1 physical interaction
relationship: participates_in CCO:I0002889 ! pir1-elp3 physical interaction
relationship: participates_in CCO:I0002890 ! cdc16-apc1-1 physical interaction
relationship: participates_in CCO:I0002906 ! arp1-tef1 physical interaction
relationship: participates_in CCO:I0002907 ! hxt4-adh1 physical interaction
relationship: participates_in CCO:I0002912 ! emp24-adh1 physical interaction
relationship: participates_in CCO:I0002918 ! kel1-bem2 physical interaction
relationship: participates_in CCO:I0002927 ! mes1-arc1 physical interaction
relationship: participates_in CCO:I0002928 ! aro1-cct8 physical interaction
relationship: participates_in CCO:I0002933 ! asp1-cdc48 physical interaction
relationship: participates_in CCO:I0002934 ! yka8-aac2 physical interaction
relationship: participates_in CCO:I0002948 ! hrb1-asc1 physical interaction
relationship: participates_in CCO:I0002953 ! siw14-eft1 physical interaction
relationship: participates_in CCO:I0002970 ! nta1-tef1 physical interaction
relationship: participates_in CCO:I0002981 ! tom70-atp2 physical interaction
relationship: participates_in CCO:I0002988 ! sec15-atp2 physical interaction
relationship: participates_in CCO:I0002995 ! ycp4-act1 physical interaction
relationship: participates_in CCO:I0002996 ! sys1-aap1 physical interaction
relationship: participates_in CCO:I0003004 ! cox9-cox4 physical interaction
relationship: participates_in CCO:I0003005 ! ykt6-pep12 physical interaction
relationship: participates_in CCO:I0003009 ! met18-aro1 physical interaction
relationship: participates_in CCO:I0003010 ! nip7-arx1 physical interaction
relationship: participates_in CCO:I0003011 ! sec5-exo84 physical interaction
relationship: participates_in CCO:I0003012 ! yg1i-act1 physical interaction
relationship: participates_in CCO:I0003013 ! yd38-adh1 physical interaction
relationship: participates_in CCO:I0003014 ! ym94-mpg1 physical interaction
relationship: participates_in CCO:I0003019 ! mot1-adh1 physical interaction
relationship: participates_in CCO:I0003022 ! pda2-kar2 physical interaction
relationship: participates_in CCO:I0003024 ! apl4-adh1 physical interaction
relationship: participates_in CCO:I0003031 ! nmd5-gcn1 physical interaction
relationship: participates_in CCO:I0003033 ! omp2-eft1-1 physical interaction
relationship: participates_in CCO:I0003044 ! yhr7-anp1 physical interaction
relationship: participates_in CCO:I0003046 ! ecm17-hsc82 physical interaction
relationship: participates_in CCO:I0003048 ! mcm16-atp2 physical interaction
relationship: participates_in CCO:I0003049 ! chc1-clc1 physical interaction
relationship: participates_in CCO:I0003051 ! ilv3-aco1 physical interaction
relationship: participates_in CCO:I0003053 ! gsh1-gfa1 physical interaction
relationship: participates_in CCO:I0003058 ! bre1-cor1 physical interaction
relationship: participates_in CCO:I0003060 ! atp3-cdc37 physical interaction
relationship: participates_in CCO:I0003061 ! ymw1-rvb1 physical interaction
relationship: participates_in CCO:I0003080 ! vps13-cmd1 physical interaction
relationship: participates_in CCO:I0003084 ! bet3-bet5 physical interaction
relationship: participates_in CCO:I0003088 ! apc5-adh1 physical interaction
relationship: participates_in CCO:I0003089 ! yk70-adh1 physical interaction
relationship: participates_in CCO:I0003094 ! pho81-cyr1 physical interaction
relationship: participates_in CCO:I0003096 ! ssk1-act1 physical interaction
relationship: participates_in CCO:I0003101 ! yeh1-kap123 physical interaction
relationship: participates_in CCO:I0003111 ! pri2-mpg1 physical interaction
relationship: participates_in CCO:I0003113 ! ixr1-abf2 physical interaction
relationship: participates_in CCO:I0003123 ! ded81-cct4 physical interaction
relationship: participates_in CCO:I0003127 ! gsf2-mpg1 physical interaction
relationship: participates_in CCO:I0003128 ! gpt2-kap123 physical interaction
relationship: participates_in CCO:I0003137 ! uba1-gfa1 physical interaction
relationship: participates_in CCO:I0003139 ! erv25-acp1 physical interaction
relationship: participates_in CCO:I0003141 ! yeu3-tub1 physical interaction
relationship: participates_in CCO:I0003147 ! yor3311c-tub1 physical interaction
relationship: participates_in CCO:I0003149 ! mcm5-gcn20 physical interaction
relationship: participates_in CCO:I0003151 ! med7-ada2 physical interaction
relationship: participates_in CCO:I0003153 ! msn5-adh1 physical interaction
relationship: participates_in CCO:I0003154 ! msh2-hda1 physical interaction
relationship: participates_in CCO:I0003155 ! rsr1-imd4 physical interaction
relationship: participates_in CCO:I0003156 ! gpt2-adh1 physical interaction
relationship: participates_in CCO:I0003162 ! sec10-exo84 physical interaction
relationship: participates_in CCO:I0003170 ! yn86-adh1 physical interaction
relationship: participates_in CCO:I0003176 ! crd1-ded81 physical interaction
relationship: participates_in CCO:I0003177 ! apa1-aap1 physical interaction
relationship: participates_in CCO:I0003183 ! yhj6-hsc82 physical interaction
relationship: participates_in CCO:I0003185 ! ilv2-dnm1 physical interaction
relationship: participates_in CCO:I0003191 ! mrs4-aac2 physical interaction
relationship: participates_in CCO:I0003193 ! ilv1-hsp60 physical interaction
relationship: participates_in CCO:I0003196 ! skn7-gfa1 physical interaction
relationship: participates_in CCO:I0003207 ! cog8-cog1 physical interaction
relationship: participates_in CCO:I0003208 ! vps13-cmd1-1 physical interaction
relationship: participates_in CCO:I0003212 ! mrpl22-asc1 physical interaction
relationship: participates_in CCO:I0003231 ! ape2-aco1-1 physical interaction
relationship: participates_in CCO:I0003232 ! srp102-srp101 physical interaction
relationship: participates_in CCO:I0003235 ! cyc3-eno2 physical interaction
relationship: participates_in CCO:I0003239 ! srp54-bem2 physical interaction
relationship: participates_in CCO:I0003247 ! rad16-adh1 physical interaction
relationship: participates_in CCO:I0003250 ! sln1-adh1 physical interaction
relationship: participates_in CCO:I0003252 ! ret2-gpt2 physical interaction
relationship: participates_in CCO:I0003259 ! yij4-eft1 physical interaction
relationship: participates_in CCO:I0003266 ! snx41-mpg1 physical interaction
relationship: participates_in CCO:I0003277 ! yjg5-atp2 physical interaction
relationship: participates_in CCO:I0003299 ! kex1-aro1 physical interaction
relationship: participates_in CCO:I0003301 ! dbp6-adh1 physical interaction
relationship: participates_in CCO:I0003302 ! yoj8-eft1 physical interaction
relationship: participates_in CCO:I0003303 ! ald2-ssa2 physical interaction
relationship: participates_in CCO:I0003304 ! mam33-eno2 physical interaction
relationship: participates_in CCO:I0003305 ! swi6-mpg1 physical interaction
relationship: participates_in CCO:I0003306 ! ym8x-aro1 physical interaction
relationship: participates_in CCO:I0003310 ! snl1-gls1 physical interaction
relationship: participates_in CCO:I0003314 ! fpr4-arx1 physical interaction
relationship: participates_in CCO:I0003316 ! rna12-adh1 physical interaction
relationship: participates_in CCO:I0003322 ! nog1-erb1 physical interaction
relationship: participates_in CCO:I0003339 ! erd2-brr2 physical interaction
relationship: participates_in CCO:I0003343 ! dbf2-pyk1 physical interaction
relationship: participates_in CCO:I0003345 ! sly41-adh1 physical interaction
relationship: participates_in CCO:I0003360 ! utp15-gcn1 physical interaction
relationship: participates_in CCO:I0003365 ! trs20-bet3-1 physical interaction
relationship: participates_in CCO:I0003366 ! yht3-ssa2 physical interaction
relationship: participates_in CCO:I0003369 ! pic2-ecm29 physical interaction
relationship: participates_in CCO:I0003371 ! mcd1-rpl17b physical interaction
relationship: participates_in CCO:I0003373 ! mam3-adh1-1 physical interaction
relationship: participates_in CCO:I0003374 ! pex13-atp2 physical interaction
relationship: participates_in CCO:I0003379 ! jsn1-mpg1 physical interaction
relationship: participates_in CCO:I0003380 ! ape2-atp2 physical interaction
relationship: participates_in CCO:I0003381 ! sec53-pyk1 physical interaction
relationship: participates_in CCO:I0003383 ! yn28-ccr4 physical interaction
relationship: participates_in CCO:I0003388 ! ptm1-anp1 physical interaction
relationship: participates_in CCO:I0003391 ! dnm1-pab1 physical interaction
relationship: participates_in CCO:I0003393 ! trp3-aha1 physical interaction
relationship: participates_in CCO:I0003399 ! lcb2-bmh1 physical interaction
relationship: participates_in CCO:I0003405 ! nif3-gfa1 physical interaction
relationship: participates_in CCO:I0003413 ! pho88-anp1 physical interaction
relationship: participates_in CCO:I0003417 ! ymc2-hsp60 physical interaction
relationship: participates_in CCO:I0003418 ! msp1-ada2 physical interaction
relationship: participates_in CCO:I0003419 ! nth1-bmh1 physical interaction
relationship: participates_in CCO:I0003422 ! yhb1-aco1 physical interaction
relationship: participates_in CCO:I0003428 ! msf1-kap123 physical interaction
relationship: participates_in CCO:I0003430 ! mba1-rpl4b physical interaction
relationship: participates_in CCO:I0003434 ! sap185-atp2 physical interaction
relationship: participates_in CCO:I0003437 ! hmg2-adh1-1 physical interaction
relationship: participates_in CCO:I0003440 ! rrp5-adh1 physical interaction
relationship: participates_in CCO:I0003443 ! yb8b-rvb2 physical interaction
relationship: participates_in CCO:I0003444 ! elo3-adh1 physical interaction
relationship: participates_in CCO:I0003446 ! ndi1-gcn1 physical interaction
relationship: participates_in CCO:I0003453 ! adh3-aco1 physical interaction
relationship: participates_in CCO:I0003455 ! arp7-act1 physical interaction
relationship: participates_in CCO:I0003457 ! q05881-adh1-1 physical interaction
relationship: participates_in CCO:I0003463 ! gcd7-ala1 physical interaction
relationship: participates_in CCO:I0003474 ! aha1-aro1 physical interaction
relationship: participates_in CCO:I0003480 ! alg12-aco1 physical interaction
relationship: participates_in CCO:I0003483 ! ura7-cpa2 physical interaction
relationship: participates_in CCO:I0003484 ! pwp1-act1-1 physical interaction
relationship: participates_in CCO:I0003488 ! ykk0-act1 physical interaction
relationship: participates_in CCO:I0003492 ! pho86-aco1 physical interaction
relationship: participates_in CCO:I0003495 ! hom2-aro1 physical interaction
relationship: participates_in CCO:I0003498 ! puf4-mpg1 physical interaction
relationship: participates_in CCO:I0003503 ! mtr10-atg3 physical interaction
relationship: participates_in CCO:I0003515 ! tub3-atp2 physical interaction
relationship: participates_in CCO:I0003519 ! nam9-gcn20 physical interaction
relationship: participates_in CCO:I0003520 ! myo3-cmd1 physical interaction
relationship: participates_in CCO:I0003521 ! prps3-eft1 physical interaction
relationship: participates_in CCO:I0003523 ! yew4-atp2 physical interaction
relationship: participates_in CCO:I0003531 ! yml6-ded1 physical interaction
relationship: participates_in CCO:I0003534 ! nmd4-adh1 physical interaction
relationship: participates_in CCO:I0003536 ! rpl23a-bcp1-1 physical interaction
relationship: participates_in CCO:I0003537 ! ufd4-aha1 physical interaction
relationship: participates_in CCO:I0003540 ! smp2-pyk1 physical interaction
relationship: participates_in CCO:I0003541 ! sam1-aco1 physical interaction
relationship: participates_in CCO:I0003545 ! dbp8-acs2 physical interaction
relationship: participates_in CCO:I0003546 ! nup192-adh1 physical interaction
relationship: participates_in CCO:I0003548 ! nup188-adh1 physical interaction
relationship: participates_in CCO:I0003554 ! rpa1-rpa12 physical interaction
relationship: participates_in CCO:I0003556 ! phr1-adh1 physical interaction
relationship: participates_in CCO:I0003568 ! yeo9-atp2 physical interaction
relationship: participates_in CCO:I0003570 ! scs7-cdc48 physical interaction
relationship: participates_in CCO:I0003573 ! myo4-act1 physical interaction
relationship: participates_in CCO:I0003577 ! phb2-ecm29 physical interaction
relationship: participates_in CCO:I0003579 ! xpo1-gcn1 physical interaction
relationship: participates_in CCO:I0003584 ! kap104-ecm29 physical interaction
relationship: participates_in CCO:I0003588 ! rgr1-cse2 physical interaction
relationship: participates_in CCO:I0003589 ! bet3-bet5-1 physical interaction
relationship: participates_in CCO:I0003592 ! idh2-idh1 physical interaction
relationship: participates_in CCO:I0003594 ! gpi17-ktr2 physical interaction
relationship: participates_in CCO:I0003617 ! yjo8-adh1 physical interaction
relationship: participates_in CCO:I0003619 ! pse1-dbp9 physical interaction
relationship: participates_in CCO:I0003620 ! rvb2-asc1 physical interaction
relationship: participates_in CCO:I0003622 ! yhb1-mpg1 physical interaction
relationship: participates_in CCO:I0003624 ! yhm1-adh1 physical interaction
relationship: participates_in CCO:I0003626 ! snx41-gcn1 physical interaction
relationship: participates_in CCO:I0003628 ! cpa2-cpa1 physical interaction
relationship: participates_in CCO:I0003633 ! yae8-adh1-1 physical interaction
relationship: participates_in CCO:I0003646 ! rpb6-gfa1 physical interaction
relationship: participates_in CCO:I0003648 ! sec16-aco1 physical interaction
relationship: participates_in CCO:I0003650 ! utp8-nan1 physical interaction
relationship: participates_in CCO:I0003651 ! fur1-kar2 physical interaction
relationship: participates_in CCO:I0003847 ! aut2-tub1 physical interaction
relationship: participates_in CCO:I0003943 ! tim50-aac2 physical interaction
relationship: participates_in CCO:I0003948 ! yn53-aof1001 physical interaction
relationship: participates_in CCO:I0003951 ! ykt5-aac2 physical interaction
relationship: participates_in CCO:I0005391 ! acs2-51 physical interaction
relationship: participates_in CCO:I0005402 ! atp2-8 physical interaction
relationship: participates_in CCO:I0005405 ! aac2-18 physical interaction
relationship: participates_in CCO:I0005423 ! ade5,7-25 physical interaction
relationship: participates_in CCO:I0005435 ! aha1-37 physical interaction
relationship: participates_in CCO:I0005454 ! atg3-3 physical interaction
relationship: participates_in CCO:I0005494 ! aac2-21 physical interaction
relationship: participates_in CCO:I0005564 ! gpi17-4 physical interaction
relationship: participates_in CCO:I0005566 ! fur1-4 physical interaction
relationship: participates_in CCO:I0005571 ! dnm1-8 physical interaction
relationship: participates_in CCO:I0005576 ! aha1-8 physical interaction
relationship: participates_in CCO:I0005584 ! aco1-9-1 physical interaction
relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation
relationship: participates_in CCO:P0000239 ! homologous chromosome segregation
relationship: transforms_into CCO:B0009614 ! TBA1_YEAST-Phosphoserine274

[Term]
id: CCO:B0000031
name: TBA3_YEAST
def: "Tubulin alpha-3 chain" [UniProtKB:P09734]
xref: EMBL:AAA35181.1
xref: EMBL:CAA89156.1
xref: UniProtKB:P09734
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002372 ! TUB3_yeast
relationship: located_in CCO:C0000386 ! spindle pole body
relationship: located_in CCO:C0000395 ! polar microtubule
relationship: located_in CCO:C0000396 ! kinetochore microtubule
relationship: located_in CCO:C0000434 ! microtubule
relationship: located_in CCO:C0000438 ! nuclear microtubule
relationship: located_in CCO:C0000439 ! cytoplasmic microtubule
relationship: located_in CCO:C0001750 ! protein complex
relationship: participates_in CCO:I0000559 ! yho3-tub3 physical interaction
relationship: participates_in CCO:I0000582 ! hmt1-tub3 physical interaction
relationship: participates_in CCO:I0002390 ! ga-165 physical interaction
relationship: participates_in CCO:I0002462 ! ga-319 physical interaction
relationship: participates_in CCO:I0002548 ! ga-531 physical interaction
relationship: participates_in CCO:I0002556 ! ga-553 physical interaction
relationship: participates_in CCO:I0002580 ! yij0-adh1 physical interaction
relationship: participates_in CCO:I0002619 ! mae1-aro1 physical interaction
relationship: participates_in CCO:I0002628 ! yhm4-asc1 physical interaction
relationship: participates_in CCO:I0002649 ! nog2-aro1 physical interaction
relationship: participates_in CCO:I0002655 ! gdh1-adh1 physical interaction
relationship: participates_in CCO:I0002684 ! acs2-asc1 physical interaction
relationship: participates_in CCO:I0002692 ! mge1-mpg1 physical interaction
relationship: participates_in CCO:I0002703 ! sap155-atp2 physical interaction
relationship: participates_in CCO:I0002774 ! puf3-mpg1 physical interaction
relationship: participates_in CCO:I0002783 ! omp2-adh1 physical interaction
relationship: participates_in CCO:I0002838 ! mak21-brx1 physical interaction
relationship: participates_in CCO:I0002870 ! rad3-asc1 physical interaction
relationship: participates_in CCO:I0002940 ! rpl18a-arx1 physical interaction
relationship: participates_in CCO:I0002945 ! mds3-cdc25 physical interaction
relationship: participates_in CCO:I0002947 ! his4-dhh1 physical interaction
relationship: participates_in CCO:I0002966 ! spt5-eft1 physical interaction
relationship: participates_in CCO:I0003039 ! rrp6-csl4 physical interaction
relationship: participates_in CCO:I0003071 ! mpg1-cct8 physical interaction
relationship: participates_in CCO:I0003106 ! fcp1-atp2 physical interaction
relationship: participates_in CCO:I0003139 ! erv25-acp1 physical interaction
relationship: participates_in CCO:I0003179 ! ynr5-arx1-1 physical interaction
relationship: participates_in CCO:I0003214 ! pdr6-atp2 physical interaction
relationship: participates_in CCO:I0003217 ! cdc60-adh1 physical interaction
relationship: participates_in CCO:I0003245 ! gcd7-aro1 physical interaction
relationship: participates_in CCO:I0003249 ! nup2-adh1 physical interaction
relationship: participates_in CCO:I0003259 ! yij4-eft1 physical interaction
relationship: participates_in CCO:I0003392 ! yeb5-dcp1-1 physical interaction
relationship: participates_in CCO:I0003393 ! trp3-aha1 physical interaction
relationship: participates_in CCO:I0003412 ! ymg7-gls1 physical interaction
relationship: participates_in CCO:I0003466 ! ald6-eft1 physical interaction
relationship: participates_in CCO:I0003515 ! tub3-atp2 physical interaction
relationship: participates_in CCO:I0003570 ! scs7-cdc48 physical interaction
relationship: participates_in CCO:I0003922 ! pho4-ade16 physical interaction
relationship: participates_in CCO:I0003951 ! ykt5-aac2 physical interaction
relationship: participates_in CCO:I0004004 ! num1-tub3 physical interaction
relationship: participates_in CCO:I0004005 ! num1-tub3-1 physical interaction
relationship: participates_in CCO:I0004332 ! yn53-grs1 physical interaction
relationship: participates_in CCO:I0005391 ! acs2-51 physical interaction
relationship: participates_in CCO:I0005435 ! aha1-37 physical interaction
relationship: participates_in CCO:I0005463 ! rpt3-tub3 physical interaction
relationship: participates_in CCO:I0005472 ! atp2-6 physical interaction
relationship: participates_in CCO:I0005473 ! cln2-18 physical interaction
relationship: participates_in CCO:I0005489 ! cct4-28 physical interaction
relationship: participates_in CCO:I0005525 ! aha1-14 physical interaction
relationship: participates_in CCO:I0005554 ! dps1-7 physical interaction
relationship: participates_in CCO:I0005562 ! gfa1-4 physical interaction
relationship: participates_in CCO:I0005604 ! emp24-11 physical interaction
relationship: participates_in CCO:I0005612 ! dps1-27 physical interaction
relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation
relationship: participates_in CCO:P0000239 ! homologous chromosome segregation

[Term]
id: CCO:B0000032
name: CDC16_YEAST
def: "Anaphase-promoting complex subunit CDC16" [UniProtKB:P09798]
synonym: "Cell division control protein 16" EXACT [UniProtKB:P09798]
xref: EMBL:CAA29521.1
xref: EMBL:CAA81857.1
xref: UniProtKB:P09798
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000278 ! CDC16_yeast
relationship: located_in CCO:C0000252 ! nucleus
relationship: located_in CCO:C0000282 ! anaphase-promoting complex
relationship: participates_in CCO:I0002326 ! ga-13 physical interaction
relationship: participates_in CCO:I0002372 ! ga-102 physical interaction
relationship: participates_in CCO:I0002574 ! doc1-act1 physical interaction
relationship: participates_in CCO:I0002591 ! cdc23-apc1 physical interaction
relationship: participates_in CCO:I0002890 ! cdc16-apc1-1 physical interaction
relationship: participates_in CCO:I0003088 ! apc5-adh1 physical interaction
relationship: participates_in CCO:I0003295 ! apc2-apc1-2 physical interaction
relationship: participates_in CCO:I0004298 ! cdc16-apc1-7 physical interaction
relationship: participates_in CCO:I0004299 ! apc2-apc1 physical interaction
relationship: participates_in CCO:I0004300 ! apc4-apc1-1 physical interaction
relationship: participates_in CCO:I0004301 ! cdc16-apc1-8 physical interaction
relationship: participates_in CCO:I0004302 ! apc2-apc1-1 physical interaction
relationship: participates_in CCO:I0004377 ! apc-comp physical interaction
relationship: participates_in CCO:I0004378 ! apc-comp-1 physical interaction
relationship: participates_in CCO:I0004379 ! apc-comp-2 physical interaction
relationship: participates_in CCO:I0004785 ! cdc16-apc1-2 physical interaction
relationship: participates_in CCO:I0004786 ! cdc16-apc1-3 physical interaction
relationship: participates_in CCO:I0004787 ! cdc27-apc1-4 physical interaction
relationship: participates_in CCO:I0004788 ! apc1-cdc16 physical interaction
relationship: participates_in CCO:I0004789 ! cdc26-cdc16-1 physical interaction
relationship: participates_in CCO:I0004790 ! cdc16-apc1-4 physical interaction
relationship: participates_in CCO:I0004791 ! apc5-apc1 physical interaction
relationship: participates_in CCO:I0004792 ! apc5-apc1-1 physical interaction
relationship: participates_in CCO:I0004793 ! cdc16-apc1-5 physical interaction
relationship: participates_in CCO:I0004794 ! cdc16-apc1-6 physical interaction
relationship: participates_in CCO:I0004795 ! apc11-apc1 physical interaction
relationship: participates_in CCO:I0004796 ! apc11-apc1-1 physical interaction
relationship: participates_in CCO:I0005149 ! ho-538 physical interaction
relationship: participates_in CCO:I0005215 ! ho-674 physical interaction
relationship: participates_in CCO:I0005278 ! cdc16-apc1 physical interaction
relationship: participates_in CCO:I0005591 ! apc1-8 physical interaction
relationship: participates_in CCO:P0000001 ! mitotic spindle elongation
relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation
relationship: participates_in CCO:P0000038 ! mitotic cell cycle
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: participates_in CCO:P0000081 ! mitosis
relationship: participates_in CCO:P0000102 ! mitotic metaphase/anaphase transition
relationship: participates_in CCO:P0000141 ! cyclin catabolic process

[Term]
id: CCO:B0000033
name: SPS4_YEAST
def: "Sporulation-specific protein 4" [UniProtKB:P09937]
xref: EMBL:AAA35081.1
xref: EMBL:CAA62168.1
xref: EMBL:CAA99633.1
xref: UniProtKB:P09937
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002233 ! SPS4_yeast
relationship: participates_in CCO:P0000117 ! meiosis

[Term]
id: CCO:B0000034
name: SWI6_YEAST
def: "Regulatory protein SWI6" [UniProtKB:P09959]
synonym: "Cell-cycle box factor subunit SWI6" EXACT [UniProtKB:P09959]
synonym: "MBF subunit P90" EXACT [UniProtKB:P09959]
synonym: "Trans-acting activator of HO endonuclease gene" EXACT [UniProtKB:P09959]
xref: EMBL:AAB67460.1
xref: EMBL:CAA29581.1
xref: UniProtKB:P09959
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002320 ! SWI6_yeast
relationship: participates_in CCO:I0001917 ! yol131w-swi6 physical interaction
relationship: participates_in CCO:I0001941 ! pet123-swi6 physical interaction
relationship: participates_in CCO:I0001943 ! sme1-swi6 physical interaction
relationship: participates_in CCO:I0002410 ! ga-215 physical interaction
relationship: participates_in CCO:I0002810 ! mbp1-rps0a physical interaction
relationship: participates_in CCO:I0002887 ! swi4-ssa1 physical interaction
relationship: participates_in CCO:I0003305 ! swi6-mpg1 physical interaction
relationship: participates_in CCO:I0005527 ! swi4-2 physical interaction
relationship: participates_in CCO:P0000013 ! G1/S-specific transcription in mitotic cell cycle
relationship: participates_in CCO:P0000117 ! meiosis
relationship: transforms_into CCO:B0009561 ! SWI6_YEAST-Phosphoserine160
relationship: transforms_into CCO:B0009562 ! SWI6_YEAST-Phosphothreonine179
relationship: transforms_into CCO:B0009563 ! SWI6_YEAST-Phosphothreonine182
relationship: transforms_into CCO:B0009564 ! SWI6_YEAST-Phosphoserine547

[Term]
id: CCO:B0000035
name: HSF_YEAST
def: "Heat shock factor protein" [UniProtKB:P10961]
synonym: "Heat shock transcription factor" EXACT [UniProtKB:P10961]
synonym: "HSF" EXACT [UniProtKB:P10961]
synonym: "HSTF" EXACT [UniProtKB:P10961]
xref: EMBL:AAA34688.1
xref: EMBL:AAA34689.1
xref: EMBL:CAA96777.1
xref: UniProtKB:P10961
xref: UniProtKB:P11529
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000842 ! HSF1_yeast
relationship: participates_in CCO:I0000967 ! ubc7-hsf1 physical interaction
relationship: participates_in CCO:P0000164 ! spindle pole body duplication
relationship: transforms_into CCO:B0007561 ! HSF_YEAST-Phosphoserine450
relationship: transforms_into CCO:B0007562 ! HSF_YEAST-Phosphothreonine460
relationship: transforms_into CCO:B0007563 ! HSF_YEAST-Phosphoserine546

[Term]
id: CCO:B0000036
name: MAK16_YEAST
def: "Protein MAK16" [UniProtKB:P10962]
synonym: "Maintenance of killer protein 16" EXACT [UniProtKB:P10962]
xref: EMBL:AAA34752.1
xref: EMBL:AAC05007.1
xref: UniProtKB:P10962
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0001073 ! MAK16_yeast
relationship: located_in CCO:C0000252 ! nucleus
relationship: located_in CCO:C0000320 ! nucleolus
relationship: participates_in CCO:I0001033 ! mak16-yjr044c physical interaction
relationship: participates_in CCO:I0003665 ! nop7-cic1 physical interaction
relationship: participates_in CCO:I0004994 ! ho-249 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle

[Term]
id: CCO:B0000037
name: CDC24_YEAST
def: "Cell division control protein 24" [UniProtKB:P11433]
synonym: "Calcium regulatory protein" EXACT [UniProtKB:P11433]
xref: EMBL:AAA82871.1
xref: EMBL:AAC04990.1
xref: UniProtKB:P11433
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000282 ! CDC24_yeast
relationship: participates_in CCO:I0001355 ! ygl052w-cdc24 physical interaction
relationship: participates_in CCO:I0001379 ! soh1-cdc24 physical interaction
relationship: participates_in CCO:I0001459 ! ygr268c-cdc24 physical interaction
relationship: participates_in CCO:I0001570 ! ykl130c-cdc24 physical interaction
relationship: participates_in CCO:I0001851 ! ymr298w-cdc24 physical interaction
relationship: participates_in CCO:I0002052 ! bem1-cdc24 physical interaction
relationship: participates_in CCO:I0002073 ! cdc24-bem1 physical interaction
relationship: participates_in CCO:I0002074 ! cdc24-cct8 physical interaction
relationship: participates_in CCO:I0002075 ! cdc24-ent2 physical interaction
relationship: participates_in CCO:I0002076 ! cdc24-far1 physical interaction
relationship: participates_in CCO:I0002077 ! cdc24-swe1 physical interaction
relationship: participates_in CCO:I0002078 ! cdc24-ygr221c physical interaction
relationship: participates_in CCO:I0002079 ! cdc24-yil079c physical interaction
relationship: participates_in CCO:I0002332 ! ga-38 physical interaction
relationship: participates_in CCO:I0002343 ! ga-57 physical interaction
relationship: participates_in CCO:I0002499 ! ga-395 physical interaction
relationship: participates_in CCO:I0002750 ! sis1-cdc24 physical interaction
relationship: participates_in CCO:I0002885 ! cdc24-boi2 physical interaction
relationship: participates_in CCO:I0003055 ! bem1-boi2 physical interaction
relationship: participates_in CCO:I0004314 ! bem1-cdc24-1 physical interaction
relationship: participates_in CCO:I0005522 ! boi2-7 physical interaction
relationship: participates_in CCO:P0000107 ! regulation of exit from mitosis
relationship: transforms_into CCO:B0006780 ! CDC24_YEAST-Phosphoserine100
relationship: transforms_into CCO:B0006781 ! CDC24_YEAST-Phosphoserine101
relationship: transforms_into CCO:B0006782 ! CDC24_YEAST-Phosphoserine729
relationship: transforms_into CCO:B0006783 ! CDC24_YEAST-Phosphothreonine738
relationship: transforms_into CCO:B0006784 ! CDC24_YEAST-Phosphoserine741

[Term]
id: CCO:B0000038
name: BIK1_YEAST
def: "Nuclear fusion protein BIK1" [UniProtKB:P11709]
xref: EMBL:AAA34614.1
xref: EMBL:CAA42356.1
xref: UniProtKB:P11709
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000178 ! BIK1_yeast
relationship: located_in CCO:C0000103 ! kinetochore
relationship: located_in CCO:C0000105 ! condensed nuclear chromosome kinetochore
relationship: located_in CCO:C0000252 ! nucleus
relationship: located_in CCO:C0000324 ! cytoplasm
relationship: located_in CCO:C0000386 ! spindle pole body
relationship: located_in CCO:C0000388 ! spindle
relationship: located_in CCO:C0000421 ! cytoskeleton
relationship: located_in CCO:C0000434 ! microtubule
relationship: located_in CCO:C0000436 ! spindle microtubule
relationship: located_in CCO:C0000489 ! cell cortex
relationship: participates_in CCO:I0000789 ! q06411-bik1 physical interaction
relationship: participates_in CCO:I0001088 ! bik1-bim1 physical interaction
relationship: participates_in CCO:I0001588 ! stu2-bik1 physical interaction
relationship: participates_in CCO:I0004267 ! kip2-bik1 physical interaction
relationship: participates_in CCO:I0004287 ! nip29-bik1 physical interaction
relationship: participates_in CCO:I0005143 ! ho-527 physical interaction
relationship: participates_in CCO:P0000001 ! mitotic spindle elongation
relationship: participates_in CCO:P0000022 ! mitotic anaphase B
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: participates_in CCO:P0000081 ! mitosis
relationship: participates_in CCO:P0000163 ! mitotic spindle organization and biogenesis in nucleus
relationship: transforms_into CCO:B0006574 ! BIK1_YEAST-Phosphoserine110

[Term]
id: CCO:B0000039
name: MCM1_YEAST
def: "Pheromone receptor transcription factor" [UniProtKB:P11746]
synonym: "GRM/PRTF protein" EXACT [UniProtKB:P11746]
xref: EMBL:AAA34609.1
xref: EMBL:AAS56311.1
xref: EMBL:CAA32389.1
xref: EMBL:CAA36691.1
xref: EMBL:CAA88409.1
xref: UniProtKB:P11746
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0001096 ! MCM1_yeast
relationship: located_in CCO:C0000117 ! nuclear chromatin
relationship: located_in CCO:C0000252 ! nucleus
relationship: participates_in CCO:I0000544 ! yg1g-mcm1 physical interaction
relationship: participates_in CCO:I0001307 ! srb4-mcm1 physical interaction
relationship: participates_in CCO:I0001815 ! mcm1-srl2 physical interaction
relationship: participates_in CCO:I0001937 ! yvc1-mcm1 physical interaction
relationship: participates_in CCO:I0003280 ! mcm1-hhf1 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle

[Term]
id: CCO:B0000040
name: TAF13_YEAST
def: "Transcription initiation factor TFIID subunit 13" [UniProtKB:P11747]
synonym: "Function unknown 81 protein" EXACT [UniProtKB:P11747]
synonym: "TAFII-19" EXACT [UniProtKB:P11747]
synonym: "TAFII19" EXACT [UniProtKB:P11747]
synonym: "TBP-associated factor 13" EXACT [UniProtKB:P11747]
synonym: "TBP-associated factor 19 kDa" EXACT [UniProtKB:P11747]
xref: EMBL:AAA34610.1
xref: EMBL:AAS56089.1
xref: EMBL:CAA86639.1
xref: UniProtKB:P11747
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002355 ! TAF13_yeast
relationship: participates_in CCO:I0001802 ! taf19-taf23 physical interaction
relationship: participates_in CCO:I0001803 ! taf19-hmo1 physical interaction
relationship: participates_in CCO:I0001804 ! taf19-yjl058c physical interaction
relationship: participates_in CCO:I0001805 ! taf19-taf40 physical interaction
relationship: participates_in CCO:I0002522 ! ga-439 physical interaction
relationship: participates_in CCO:I0002921 ! taf13-imd3 physical interaction
relationship: participates_in CCO:I0003736 ! taf11-taf13-1 physical interaction
relationship: participates_in CCO:I0003738 ! taf13-taf11-1 physical interaction
relationship: participates_in CCO:I0003741 ! spt15-taf145-2 physical interaction
relationship: participates_in CCO:I0003742 ! spt15-taf145-3 physical interaction
relationship: participates_in CCO:I0003743 ! spt15-taf145-1 physical interaction
relationship: participates_in CCO:I0003746 ! taf5-taf7-1 physical interaction
relationship: participates_in CCO:I0003890 ! taf145-tsm-1 physical interaction
relationship: participates_in CCO:I0003897 ! taf1-taf5-1 physical interaction
relationship: participates_in CCO:I0003898 ! taf1-taf5-2 physical interaction
relationship: participates_in CCO:P0000024 ! G1-specific transcription in mitotic cell cycle
relationship: transforms_into CCO:B0009596 ! TAF13_YEAST-Phosphothreonine131

[Term]
id: CCO:B0000041
name: KAR1_YEAST
def: "Cell division control protein KAR1" [UniProtKB:P11927]
xref: EMBL:AAA34716.1
xref: EMBL:CAA96082.1
xref: UniProtKB:P11927
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000967 ! KAR1_yeast
relationship: located_in CCO:C0000393 ! half bridge of spindle pole body
relationship: located_in CCO:C0000434 ! microtubule
relationship: participates_in CCO:I0000826 ! ynm4-kar1 physical interaction
relationship: participates_in CCO:I0001951 ! cdc31-kar1 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: participates_in CCO:P0000081 ! mitosis
relationship: participates_in CCO:P0000112 ! spindle pole body duplication in nuclear envelope

[Term]
id: CCO:B0000042
name: WHI2_YEAST
def: "Growth regulation protein" [UniProtKB:P12611]
xref: EMBL:AAA35218.1
xref: EMBL:CAA99234.1
xref: UniProtKB:P12611
xref: UniProtKB:Q08413
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002617 ! WHI2_yeast
relationship: participates_in CCO:I0000535 ! frq1-whi2 physical interaction
relationship: participates_in CCO:I0000557 ! yho3-whi2 physical interaction
relationship: participates_in CCO:I0000723 ! gic2-whi2 physical interaction
relationship: participates_in CCO:I0000748 ! gic1-whi2 physical interaction
relationship: participates_in CCO:I0000941 ! ubc7-whi2 physical interaction
relationship: participates_in CCO:I0001926 ! whi2-ydr061w physical interaction
relationship: participates_in CCO:I0001927 ! whi2-akr1 physical interaction
relationship: participates_in CCO:I0001928 ! whi2-prs5 physical interaction
relationship: participates_in CCO:I0001929 ! whi2-psr1 physical interaction
relationship: participates_in CCO:I0001930 ! whi2-psr2 physical interaction
relationship: participates_in CCO:I0003789 ! whi2-psr1-1 physical interaction
relationship: participates_in CCO:I0004835 ! whi2-psr1-2 physical interaction
relationship: participates_in CCO:I0004836 ! whi2-msn2 physical interaction
relationship: participates_in CCO:I0004858 ! ho-16 physical interaction
relationship: participates_in CCO:I0004925 ! ho-132 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: transforms_into CCO:B0009876 ! WHI2_YEAST-Phosphoserine130
relationship: transforms_into CCO:B0009877 ! WHI2_YEAST-Phosphoserine131
relationship: transforms_into CCO:B0009878 ! WHI2_YEAST-Phosphoserine380
relationship: transforms_into CCO:B0009879 ! WHI2_YEAST-Phosphoserine386

[Term]
id: CCO:B0000043
name: RAD50_YEAST
def: "DNA repair protein RAD50" [UniProtKB:P12753]
synonym: "153 kDa protein" EXACT [UniProtKB:P12753]
synonym: "EC 3.6.-.-" EXACT [UniProtKB:P12753]
xref: EMBL:CAA32919.1
xref: EMBL:CAA65494.1
xref: EMBL:CAA96157.1
xref: UniProtKB:P12753
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0001651 ! RAD50_yeast
relationship: located_in CCO:C0000252 ! nucleus
relationship: located_in CCO:C0000296 ! chromosome
relationship: located_in CCO:C0000325 ! mitochondrion
relationship: located_in CCO:C0001060 ! Mre11 complex
relationship: participates_in CCO:I0002457 ! ga-310 physical interaction
relationship: participates_in CCO:I0002715 ! ies5-arp5 physical interaction
relationship: participates_in CCO:I0003034 ! idp1-bre5 physical interaction
relationship: participates_in CCO:I0003065 ! rad50-rpn11 physical interaction
relationship: participates_in CCO:I0003103 ! tsc13-rad50 physical interaction
relationship: participates_in CCO:I0003204 ! ptc3-eft1 physical interaction
relationship: participates_in CCO:I0004125 ! inh1-rad50 physical interaction
relationship: participates_in CCO:I0004139 ! ym06-rad50 physical interaction
relationship: participates_in CCO:I0004221 ! nnf1-rad50 physical interaction
relationship: participates_in CCO:I0004234 ! nnf1-rad50-1 physical interaction
relationship: participates_in CCO:I0004255 ! rad50-smc1 physical interaction
relationship: participates_in CCO:I0004256 ! rad50-nuf2 physical interaction
relationship: participates_in CCO:I0004257 ! rad50-hda2 physical interaction
relationship: participates_in CCO:I0004258 ! rad50-end3 physical interaction
relationship: participates_in CCO:I0004259 ! rad50-rad50 physical interaction
relationship: participates_in CCO:I0004260 ! rad50-rad50-1 physical interaction
relationship: participates_in CCO:I0005041 ! ho-341 physical interaction
relationship: participates_in CCO:I0005163 ! ho-562 physical interaction
relationship: participates_in CCO:I0005202 ! ho-637 physical interaction
relationship: participates_in CCO:I0005215 ! ho-674 physical interaction
relationship: participates_in CCO:I0005441 ! cdc6-41 physical interaction
relationship: participates_in CCO:I0005483 ! bre5-8 physical interaction
relationship: participates_in CCO:I0005504 ! abf2-25 physical interaction
relationship: participates_in CCO:I0005542 ! act1-19 physical interaction
relationship: participates_in CCO:I0005544 ! paa1-8 physical interaction
relationship: participates_in CCO:P0000044 ! meiotic DNA double-strand break processing
relationship: participates_in CCO:P0000117 ! meiosis
relationship: participates_in CCO:P0000228 ! meiotic DNA double-strand break formation

[Term]
id: CCO:B0000044
name: TOP3_YEAST
def: "DNA topoisomerase 3" [UniProtKB:P13099]
synonym: "DNA topoisomerase III" EXACT [UniProtKB:P13099]
synonym: "EC 5.99.1.2" EXACT [UniProtKB:P13099]
xref: EMBL:AAA35161.1
xref: EMBL:AAB67406.1
xref: UniProtKB:P13099
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002441 ! TOP3_yeast
relationship: located_in CCO:C0000252 ! nucleus
relationship: located_in CCO:C0000296 ! chromosome
relationship: located_in CCO:C0001242 ! RecQ helicase-Topo III complex
relationship: participates_in CCO:I0001454 ! ygr239c-top3 physical interaction
relationship: participates_in CCO:I0002309 ! top3-dun1 physical interaction
relationship: participates_in CCO:I0002423 ! ga-234 physical interaction
relationship: participates_in CCO:I0003287 ! msh6-lcd1 physical interaction
relationship: participates_in CCO:P0000122 ! meiotic recombination

[Term]
id: CCO:B0000045
name: SS100_YEAST
def: "Sporulation-specific wall maturation protein precursor" [UniProtKB:P13130]
xref: EMBL:AAA35082.1
xref: EMBL:AAB68419.1
xref: EMBL:CAA73952.1
xref: UniProtKB:P13130
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0002257 ! SPS100_yeast
relationship: participates_in CCO:P0000117 ! meiosis

[Term]
id: CCO:B0000046
name: CG13_YEAST
def: "G1/S-specific cyclin CLN3" [UniProtKB:P13365]
xref: EMBL:AAA34551.1
xref: EMBL:AAA34552.1
xref: EMBL:AAC04991.1
xref: EMBL:CAA32143.1
xref: UniProtKB:P13365
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000313 ! CLN3_yeast
relationship: located_in CCO:C0000252 ! nucleus
relationship: participates_in CCO:I0000699 ! cdc28-cln3-1 physical interaction
relationship: participates_in CCO:I0002082 ! cdc28-cln3 physical interaction
relationship: participates_in CCO:I0002127 ! cln3-cdc28 physical interaction
relationship: participates_in CCO:I0002128 ! cln3-nmd5 physical interaction
relationship: participates_in CCO:I0002129 ! cln3-pac1 physical interaction
relationship: participates_in CCO:I0002130 ! cln3-spa2 physical interaction
relationship: participates_in CCO:I0002131 ! cln3-ypl014w physical interaction
relationship: participates_in CCO:I0004430 ! cln3-mad3 physical interaction
relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle
relationship: participates_in CCO:P0000066 ! cell cycle

[Term]
id: CCO:B0000047
name: RSR1_YEAST
def: "Ras-related protein RSR1 precursor" [UniProtKB:P13856]
xref: EMBL:AAA35013.1
xref: EMBL:CAA59809.1
xref: EMBL:CAA97166.1
xref: UniProtKB:P13856
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0001976 ! RSR1_yeast
relationship: participates_in CCO:I0001075 ! ybr207w-rsr1 physical interaction
relationship: participates_in CCO:I0002263 ! rsr1-bem4 physical interaction
relationship: participates_in CCO:I0003155 ! rsr1-imd4 physical interaction
relationship: participates_in CCO:P0000066 ! cell cycle
relationship: transforms_into CCO:B0009032 ! RSR1_YEAST-Cysteine methyl ester269

[Term]
id: CCO:B0000048
name: CHS2_YEAST
def: "Chitin synthase 2" [UniProtKB:P14180]
synonym: "Chitin-UDP acetyl-glucosaminyl transferase 2" EXACT [UniProtKB:P14180]
synonym: "EC 2.4.1.16" EXACT [UniProtKB:P14180]
xref: EMBL:AAA34493.1
xref: EMBL:CAA84980.1
xref: UniProtKB:P14180
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0000327 ! CHS2_yeast
relationship: located_in CCO:C0000487 ! cellular bud neck
relationship: located_in CCO:C0000766 ! membrane
relationship: located_in CCO:C0000767 ! integral to membrane
relationship: participates_in CCO:I0000678 ! yjy3-chs2 physical interaction
relationship: participates_in CCO:I0001087 ! ycl022c-chs2 physical interaction
relationship: participates_in CCO:I0001482 ! ept1-chs2 physical interaction
relationship: participates_in CCO:I0001990 ! ulp1-chs2 physical interaction
relationship: participates_in CCO:I0002036 ! isr1-chs2 physical interaction
relationship: participates_in CCO:I0002806 ! chs2-act1 physical interaction
relationship: participates_in CCO:P0000060 ! contractile ring contraction involved in cytokinesis
relationship: transforms_into CCO:B0006818 ! CHS2_YEAST-Phosphoserine14
relationship: transforms_into CCO:B0006819 ! CHS2_YEAST-Phosphoserine69
relationship: transforms_into CCO:B0006820 ! CHS2_YEAST-Phosphoserine82
relationship: transforms_into CCO:B0006821 ! CHS2_YEAST-Phosphoserine86
relationship: transforms_into CCO:B0006822 ! CHS2_YEAST-Phosphoserine100
relationship: transforms_into CCO:B0006823 ! CHS2_YEAST-Phosphoserine133
relationship: transforms_into CCO:B0006824 ! CHS2_YEAST-Phosphoserine217

[Term]
id: CCO:B0000049
name: PMS1_YEAST
def: "DNA mismatch repair protein PMS1" [UniProtKB:P14242]
synonym: "Postmeiotic segregation protein 1" EXACT [UniProtKB:P14242]
xref: EMBL:AAA34885.1
xref: EMBL:AAM00521.1
xref: EMBL:AAM00533.1
xref: EMBL:AAM00545.1
xref: EMBL:AAM00551.1
xref: EMBL:AAM00563.1
xref: EMBL:AAM00569.1
xref: EMBL:AAZ22526.1
xref: EMBL:ABC86932.1
xref: EMBL:ABC86933.1
xref: EMBL:ABC86934.1
xref: EMBL:ABC86935.1
xref: EMBL:ABC86936.1
xref: EMBL:CAA60176.1
xref: EMBL:CAA61428.1
xref: EMBL:CAA95956.1
xref: EMBL:CAA95957.1
xref: UniProtKB:P14242
xref: UniProtKB:Q2I044
xref: UniProtKB:Q2I045
xref: UniProtKB:Q45TY4
xref: UniProtKB:Q8TG48
xref: UniProtKB:Q8TG50
xref: UniProtKB:Q8TG54
xref: UniProtKB:Q8TG57
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0001504 ! PMS1_yeast
relationship: participates_in CCO:I0000807 ! atg12-pms1 physical interaction
relationship: participates_in CCO:I0000926 ! ubc7-pms1 physical interaction
relationship: participates_in CCO:I0002416 ! ga-225 physical interaction
relationship: participates_in CCO:I0002446 ! ga-286 physical interaction
relationship: participates_in CCO:I0002869 ! mlh1-pms1 physical interaction
relationship: participates_in CCO:I0003424 ! pms1-mlh1 physical interaction
relationship: participates_in CCO:I0003784 ! mlh1-pms1-1 physical interaction
relationship: participates_in CCO:I0004828 ! mlh1-pms1-2 physical interaction
relationship: participates_in CCO:I0004829 ! mlh1-pms1-3 physical interaction
relationship: participates_in CCO:I0005528 ! mlh1-3 physical interaction
relationship: participates_in CCO:P0000048 ! meiotic mismatch repair
relationship: transforms_into CCO:B0008547 ! PMS1_YEAST-Phosphoserine393

[Term]
id: CCO:B0000050
name: RED1_YEAST
def: "Protein RED1" [UniProtKB:P14291]
synonym: "Reductional division protein 1" EXACT [UniProtKB:P14291]
xref: EMBL:AAB67376.1
xref: EMBL:CAA34306.1
xref: UniProtKB:P14291
is_a: CCO:B0000000 ! core cell cycle protein
relationship: belongs_to CCO:T0000016 ! Saccharomyces cerevisiae organism
relationship: encoded_by CCO:G0001686 ! RED1_yeast
relationship: located_in CCO:C0000127 ! lateral element
relationship: located_in CCO:C0000252 ! nucleus
relationship: participates_in CCO:I0000927 ! ubc7-red1 physical interaction
relationship: participates_in CCO:I0001605 ! red1-smt3 physical interaction
relationship: participates_in CCO:I0001606 ! red1-ylr064w physical interaction
relationship: participates_in CCO:I0005205 ! ho-647 physical interaction
relationship: participates_in CCO:P0000117 ! meiosis
relationship: participates_in CCO:P0000121 ! synaptonemal complex assembly
relationship: participates_in CCO:P0000122 ! meiotic recombination
relationship: participates_in CCO:P0000345 ! meiotic recombination checkpoint

[Term]
id: CCO:B0000051
name: KSS1_YEAST
def: "Mitogen-activated protein kinase KSS1" [UniProtKB:P14681]
synonym: "EC 2.7.11.24" EXACT [UniProtKB:P14681]
synonym: "Kinase suppressor of SST2" EXACT [UniProtKB:P14681]
synonym: "MAP kinase KSS1" EXACT [UniProtKB:P14681]
xref: EMBL:AAA34882.1
xref: EMBL:AAS56099.1
xref: EMBL:AAZ22456.1
xref: EMBL:CAA97038.1
xref: UniProtKB:P14681
xref: UniProtKB:Q45U43
is_a: CCO:B0000000 ! core cell cycle protein
re