Protégé is a free, open source ontology editor and knowledge-base framework. The Protégé platform supports two main ways of modeling ontologies via the Protégé-Frames and Protégé-OWL editors. Protégé ontologies can be exported into a variety of formats including RDF(S), OWL, and XML Schema. (more) Protégé is based on Java, is extensible, and provides a plug-and-play environment that makes it a flexible base for rapid prototyping and application development. (more)
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The National Center for Biomedical Ontology is one of the National Centers for Biomedical Computing supported by the NIH Roadmap.
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