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	<id>https://www.bioontology.org//mediawiki/index.php?action=history&amp;feed=atom&amp;title=Degrees_of_Annotation</id>
	<title>Degrees of Annotation - Revision history</title>
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	<updated>2026-06-05T22:22:32Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://www.bioontology.org//mediawiki/index.php?title=Degrees_of_Annotation&amp;diff=3182&amp;oldid=prev</id>
		<title>Cjm2 at 23:15, 15 May 2006</title>
		<link rel="alternate" type="text/html" href="https://www.bioontology.org//mediawiki/index.php?title=Degrees_of_Annotation&amp;diff=3182&amp;oldid=prev"/>
		<updated>2006-05-15T23:15:33Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table class=&quot;diff diff-contentalign-left diff-editfont-monospace&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 23:15, 15 May 2006&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l4&quot; &gt;Line 4:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 4:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;In the context of the bio* domain, annotation referes to some descriptive text that assists in the interpretation of the primary information [about an item] at hand. There can be various levels of annotation for example:&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;In the context of the bio* domain, annotation referes to some descriptive text that assists in the interpretation of the primary information [about an item] at hand. There can be various levels of annotation for example:&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;* If the &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;sequence trace &lt;/del&gt;coming out of a &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;sequencer &lt;/del&gt;is the primary information then the assignment of &amp;quot;labels&amp;quot; such as 'start site', 'exon', 'intron' to different parts of the sequence is an annotation.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;* If the &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;assembled genome &lt;/ins&gt;coming out of a &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;sequence assembly program &lt;/ins&gt;is the primary information then the assignment of &amp;quot;labels&amp;quot; such as 'start site', 'exon', 'intron' to different parts of the sequence is an annotation.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;* At the second level this annotation itself [the statement about the boundries of 'start site', 'exon', 'intron'] is a conceptual item called a gene. Which is further &amp;quot;annotated&amp;quot; to have a particular 'function' or 'location' in the cell.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;* At the second level this annotation itself [the statement about the boundries of 'start site', 'exon', 'intron'] is a conceptual item called a gene. Which is further &amp;quot;annotated&amp;quot; to have a particular 'function' or 'location' in the cell.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l11&quot; &gt;Line 11:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 11:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;so defining the boundry between an information item (or data) and an annotation is dependent on the use case.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;so defining the boundry between an information item (or data) and an annotation is dependent on the use case.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Note from cjm: I have minor disagreements with most of the above. I think in the bio* domain annotations are much more than descriptive text. It is typically highly structured data. I think this is glossing over a lot - from base calling through assemblies and compute pipelines (the results of which are sometimes called annotations, although the word is typically only used for human-curated data). As well as simply labeling, there is a lot more going on with annotating intron-exon structure before functional annotation even starts. Why are genes conceptual items and exons aren't? Not sure what the final point means. But yes, the basic idea that annotation refers to different things at different levels is correct, so we should ban use of the word annotation as it is inherently ambiguous.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;

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		<author><name>Cjm2</name></author>
	</entry>
	<entry>
		<id>https://www.bioontology.org//mediawiki/index.php?title=Degrees_of_Annotation&amp;diff=1666&amp;oldid=prev</id>
		<title>Nigam at 19:22, 21 November 2005</title>
		<link rel="alternate" type="text/html" href="https://www.bioontology.org//mediawiki/index.php?title=Degrees_of_Annotation&amp;diff=1666&amp;oldid=prev"/>
		<updated>2005-11-21T19:22:54Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table class=&quot;diff diff-contentalign-left diff-editfont-monospace&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 19:22, 21 November 2005&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot; &gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;quot;Annotation&amp;quot; has various definitions. One of them is&lt;del class=&quot;diffchange diffchange-inline&quot;&gt;:&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;quot;Annotation&amp;quot; has various definitions. One of them &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;(from wikipedia) &lt;/ins&gt;is &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;-&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Annotation is information associated with a particular point [or item] in a document or other piece of information.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Annotation is information associated with a particular point [or item] in a document or other piece of information.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;

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		<author><name>Nigam</name></author>
	</entry>
	<entry>
		<id>https://www.bioontology.org//mediawiki/index.php?title=Degrees_of_Annotation&amp;diff=1665&amp;oldid=prev</id>
		<title>Nigam at 19:22, 21 November 2005</title>
		<link rel="alternate" type="text/html" href="https://www.bioontology.org//mediawiki/index.php?title=Degrees_of_Annotation&amp;diff=1665&amp;oldid=prev"/>
		<updated>2005-11-21T19:22:04Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;quot;Annotation&amp;quot; has various definitions. One of them is:&lt;br /&gt;
Annotation is information associated with a particular point [or item] in a document or other piece of information.&lt;br /&gt;
&lt;br /&gt;
In the context of the bio* domain, annotation referes to some descriptive text that assists in the interpretation of the primary information [about an item] at hand. There can be various levels of annotation for example:&lt;br /&gt;
&lt;br /&gt;
* If the sequence trace coming out of a sequencer is the primary information then the assignment of &amp;quot;labels&amp;quot; such as 'start site', 'exon', 'intron' to different parts of the sequence is an annotation.&lt;br /&gt;
&lt;br /&gt;
* At the second level this annotation itself [the statement about the boundries of 'start site', 'exon', 'intron'] is a conceptual item called a gene. Which is further &amp;quot;annotated&amp;quot; to have a particular 'function' or 'location' in the cell.&lt;br /&gt;
&lt;br /&gt;
* At a still higher level this annotation [about the function or location] is an item that is &amp;quot;annotated&amp;quot; to be relevant only in a certain genetic or experimental context.&lt;br /&gt;
&lt;br /&gt;
so defining the boundry between an information item (or data) and an annotation is dependent on the use case.&lt;/div&gt;</summary>
		<author><name>Nigam</name></author>
	</entry>
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