Clinical and Translational Science Ontology Workshop

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The National Center for Biomedical Ontology will hold a Clinical and Translational Science Ontology Tutorial and Workshop in its series of training and dissemination events.

The Tutorial will provide a beginners' introduction to ontology technology relevant to clinical and translational scientists. Topics highlighted in the tutorial will be of particular interest to individuals at institutions conducting clinical and translational research, including institutions who have or are interested in obtaining CTSA (Clinical and Translational Science Award) grants.

The Workshop will provide an opportunity for those involved in ontology-related projects within and beyond the CTSA Consortium to review what has been achieved thus far and consider plans and strategies for enhanced coordination in the future. It will feature presentations of on-going work on ontology-supported research at CTSA Consortium institutions.

Venue: Hilton Garden Inn Baltimore Airport


Tutorial: April 24, 2012
Workshop: April 25-26, 2012

Organization: Barry Smith (NCBO), Jessica Tenenbaum (Duke), Rob Wynden (UCSF)

Tutorial (Tuesday, April 24)

Introduction to Biomedical Ontology for Non-Experts
Foundations of Biomedical Ontology
What is an ontology and what is it useful for?
The problem of data silos
NIH mandates for sharing and reuse of research data
Examples of biomedical ontologies:
  • Gene Ontology (GO)
  • Foundational Model of Anatomy (FMA)
  • Infectious Disease Ontology (IDO)
Ontology Technology
An Introduction to the Semantic Web and the Web Ontology Language (OWL)
Using ontologies for data retrieval, integration and reasoning
Success stories
Basic information on ontology editing tools and on use of Bioportal

Workshop (Day 1: Wednesday, April 25)

Major Ontology Initiatives relevant to Clinical and Translational Research
Chris Chute (Mayo): Data Governance and Normalization within the Mayo Clinic Enterprise
Melissa Haendel (Oregon) and Jon Corson-Rikert (Cornell): eagle-i and VIVO Ontology Initiatives
Jessica Tenenbaum (Duke): Remarks on Genetics Ontologies 
William Hogan (Arkansas) and Werner Ceusters (Buffalo): Referent Tracking and Demographic Data Ontology
Shawn Murphy (Partners): i2b2-Specific Ontologies
Richard Scheuermann and Lindsay Cowell (Dallas): NLP-Based Mapping of Textbook Pathology to Ontology for General Medical Science (OGMS)
Possibly also: OCRe (for clinical research), Permissions Ontology (for consent; owned by Jihad Obeid at Medical University of South Carolina); biobanking ontology (Arkansas)

Workshop (Day 2: Thursday, April 26)

EHR, Ontology and Interoperability
Presentations by EHR vendors
Rob Wynden (UCSF): The Health Ontology Mapper (HOM).
Next Steps
How can we measure the value brought by ontology-based approaches?
How can we ensure high-quality and high-value approaches?
How can we promote a consistent approach across the CTSA consortium?