Difference between revisions of "OntologyRelations"

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(Guidelines and Goals)
(Biochemical (Mike B))
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* homologous_to & evo_derives_from
* homologous_to & evo_derives_from
=== Biochemical (Mike B) ===  
=== Biochemical (Larry / Mike B) ===  
* pathways (BioPAX-OBO, AlanR)
* pathways (BioPAX-OBO, AlanR)
* review bp_xp_chebi (Bada)
* review bp_xp_chebi (Bada)
* Molecular interactions and the PSI-MI relation(esque) terms. (Bada)
* Molecular interactions and the PSI-MI relation(esque) terms. (Larry)
=== Epistemic (Larry) ===  
=== Epistemic (Larry) ===  

Revision as of 17:31, 16 April 2008

Workshop on the Relationship Ontology

The National Center for Biomedical Ontology will host a two-day workshop focused on the relationship between terms (classes) in ontologies.


Guidelines and Goals

  • Our over-arching guiding principle is to keep the Relations Ontology biology driven. This means that any relations proposed must be kept:
    • simple, with well-thought out definitions
    • example-driven, that is an instance-level definition must exist (see RO paper)
    • expressed in a clear, consistent symbol-free syntax
  • The goals of this workshop are to develop the content of the relationship ontology. By the end of the meeting we hope to complete all of the following:
    • All outstanding items on the request tracking system are solved
    • All relations in ro_proposed are "blessed" and move into RO proper
    • A release of the cross-product (xp) files is generated
    • We will produce a new release of the RO


  • The leader of each session topic should be prepared to provide a summary of the issues involved and the available choices to be decided upon
  • Leaders should recommend papers to read in preparation and send out PDFs for CS folks and biologistsd
  • Nomi Harris and Chris Mungall are working to ensure that OBO-Edit2 will be fit to use during the workshop so that we can use it to immediately modify the RO

Agenda: 8:00AM-5:30PM Monday, May 19th 2008

General (Barry/Chris)

  • review of principles
    • all-some(time) (Barry)
    • desired level of granularity (Barry)
  • review of website, tracker (Chris)
    • process for adding terms
  • review of current primary representation in .obo, .owl conversion (Chris)
  • ID policy (BFO), ontology lifecycle issues etc
  • cross-products

Development and anatomy (DavidOS)

  • stages and temporal relations
    • DavidOS/Fabian
    • Interval calculus
    • ZFA stages use case: start, end
  • develops_from (Melissa)
  • relations from CARO paper (Fabian)
  • review biological_process_xp_cell (Chris/MikeB)
  • replaced_by - endochondral bone replaces cartilege (Wasila)
  • agent_in - is it valid? "heart process" example - DavidH/Chris

Biological qualities and phenotypes (Chris)

  • lacks_part (Werner)
  • inheres_in
    • relational qualities
      • towards relation
      • relational qualities and relations - what's the difference. lacks_part example
  • relations between qualities, comparisons and abnormality

Spatial relations (Melissa/Suzi)

  • surrounded_by
  • overlaps - bone + joint use case (Melissa)
  • connected_to - axon tracts and neuropil (fiat binary)
  • attached_to - bone + bone use case (Melissa)
  • RCC8 - can we just import directly?
  • bona fide vs fiat - when does it matter
  • spatial.obo

Regulation (David/Tanya/Chris)

Agenda: 8:00AM-3:30PM Tuesday, May 20th 2008

Evolutionary (Melissa & Wasila)

  • homologous_to & evo_derives_from

Biochemical (Larry / Mike B)

  • pathways (BioPAX-OBO, AlanR)
  • review bp_xp_chebi (Bada)
  • Molecular interactions and the PSI-MI relation(esque) terms. (Larry)

Epistemic (Larry)

  • supported_by et al

Logical/representation issues

  • FOL representations of RO (Thom & Fabian)
  • RO and BFO
  • OBO and OWL issues (Alan, Chris, Nigam)
  • instance vs type level; punning vs separate IDs
  • the time issue. OWL representation (Alan)
  • ternary relations in RO: DavidS's use case (DavidOS/Chris)
  • Erick's list of meta-relations
  • idiosyncratic relations in the FMA (Suzi/Nigam)


  • If you need advice or want to talk to someone regarding logistics, email Kathy Thomas and mention the Relation Ontology expert meeting in May.

Invited Participants

Confirmed (alphabetically)

  1. Mike Bada (host / Denver, CO)
  2. Tanya Berardini (TAIR / Stanford, CA)
  3. Bill Bug (BIRN / San Diego, CA)
  4. Werner Ceusters (ORG / Buffalo, NY)
  5. Wasila Dahdul (NESCENT)
  6. Mary Dolan (MGI / Bar Harbor, ME)
  7. Melissa Haendel (ZFIN / Eugene, OR)
  8. David Hill (MGI / Bar Harbor, ME)
  9. Larry Hunter (host / Denver, CO)
  10. Suzi Lewis (NCBO / Berkeley, CA)
  11. Peter Midford (NESCent)
  12. Chris Mungall (Flybase / Berkeley, CA)
  13. Darren Natale (PRO / Georgetown, Washington, DC)
  14. Fabian Neuhaus (NIST / Washington, DC)
  15. David Osumi-Sutherland (FlyBase / Cambridge, UK)
  16. Cornelius Rosse (FMA / Seattle, WA)
  17. Alan Ruttenberg (Science Commons / Cambridge, MA)
  18. Nigam Shah (NCBO / Stanford, CA)
  19. Barry Smith (NCBO / Buffalo, NY)


  1. Thomas Bittner (ORG / Buffalo, NY)
  2. Waclaw Kusnierczyk (Bergen, Norway)

Background Material

Relation Ontology Home

Current Proposals for new relations

Personal tools