Difference between revisions of "PRO"

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m (New page: The Kick-0ff Meeting of the Protein Ontology project will take place in Georgetown University on November 7-9, 2007. A draft program is as follows: '''Wednesday, November 7''' Arrival of...)
 
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The Kick-0ff Meeting of the Protein Ontology project will take place in Georgetown University on November 7-9, 2007.
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== Protein Ontology Kick-Off Meeting ==
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The inaugural meeting of the Protein Ontology project will take place in Georgetown University on November 7-9, 2007. This is an internal meeting. Its goals are to subject the PRO ontology to preliminary critique and to establish plans for its further development, dissemination and use.
  
 
A draft program is as follows:
 
A draft program is as follows:
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Location:  
 
Location:  
  
8:30am Continental Breakfast
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8:30am Continental Breakfast
  
9:00am-10:30am Session 1: Introduction to the Protein Ontology (Cathy Wu)
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9:00am-10:30am Session 1: Introduction to the Protein Ontology (Cathy Wu)
  
 
10:45am-12:15pm Session 2: The Protein Ontology and Its Neighbors (Darren Natale)
 
10:45am-12:15pm Session 2: The Protein Ontology and Its Neighbors (Darren Natale)
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12:15pm- 1:30pm Lunch
 
12:15pm- 1:30pm Lunch
  
1:30pm- 3:00pm Session 3: The Protein Ontology within the OBO Foundry (Barry Smith)
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1:30pm- 3:00pm Session 3: The Protein Ontology within the OBO Foundry (Barry Smith)
  
3:30pm- 5:00pm Session 4: Protein Ontology and Protein Data (Chris Mungall and Alan Ruttenberg)
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3:30pm- 5:00pm Session 4: Protein Ontology and Protein Data (Chris Mungall and Alan Ruttenberg)
  
6:00pm Dinner [Location to be Announced]
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6:00pm Dinner [Location to be Announced]
  
 
'''Friday, November 9'''
 
'''Friday, November 9'''
 
Location: ??
 
Location: ??
  
8:30am Continental Breakfast
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8:30am Continental Breakfast
  
9:00am-10:30am Session 5: The Protein Ontology and Its Users 1 (Helen Berman)
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9:00am-10:30am Session 5: The Protein Ontology and Its Users 1 (Helen Berman)
  
 
10:45am-12:15pm Session 6: The Protein Ontology and Its Users 2 (Judith Blake)
 
10:45am-12:15pm Session 6: The Protein Ontology and Its Users 2 (Judith Blake)
  
1:30pm- 4:00pm Session 8: Next Steps (Suzanna Lewis)
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1:30pm- 4:00pm Session 8: Next Steps (Suzanna Lewis)
  
  
 
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== Protein Ontology Specific Aims ==
  
  

Revision as of 11:08, 27 July 2007

Protein Ontology Kick-Off Meeting

The inaugural meeting of the Protein Ontology project will take place in Georgetown University on November 7-9, 2007. This is an internal meeting. Its goals are to subject the PRO ontology to preliminary critique and to establish plans for its further development, dissemination and use.

A draft program is as follows:

Wednesday, November 7 Arrival of Workshop Participants Dinner for Workshop Participants [Time/Location to be Announced]

Thursday, November 8 Location:

8:30am Continental Breakfast

9:00am-10:30am Session 1: Introduction to the Protein Ontology (Cathy Wu)

10:45am-12:15pm Session 2: The Protein Ontology and Its Neighbors (Darren Natale)

12:15pm- 1:30pm Lunch

1:30pm- 3:00pm Session 3: The Protein Ontology within the OBO Foundry (Barry Smith)

3:30pm- 5:00pm Session 4: Protein Ontology and Protein Data (Chris Mungall and Alan Ruttenberg)

6:00pm Dinner [Location to be Announced]

Friday, November 9 Location: ??

8:30am Continental Breakfast

9:00am-10:30am Session 5: The Protein Ontology and Its Users 1 (Helen Berman)

10:45am-12:15pm Session 6: The Protein Ontology and Its Users 2 (Judith Blake)

1:30pm- 4:00pm Session 8: Next Steps (Suzanna Lewis)



Protein Ontology Specific Aims

The Protein Ontology (PRO) project is funded by NIGMS / NIH Grant 1 R01 GM080646-01, PI: Cathy Wu. The Aims of the project are:

Aim 1. Develop a Protein Evolution (ProEvo) ontology to describe proteins based on evolutionary relationships. In essence, ProEvo will reflect protein families (using sequence or structure similarities) in an ontology framework.

Aim 2. Develop a Protein Forms (ProForm) ontology to represent the multiple protein end-products from a gene. This will include "normal" and mutant forms, forms derived from different splice variants, and cleaved and post-translationally modified products.

Aim 3. Specify the relationships between the ProEvo, ProMod and other OBO Foundry ontologies. Several ontologies provide qualities that can be attributed to various forms of a protein or to an entire protein family. These qualities, in effect, can annotate the protein forms or families.

Aim 4. Disseminate PRO ontology, and demonstrate its usefulness in health-related research via scientific case studies.

Literature : Darren A. Natale, Cecilia N. Arighi, Winona Barker, Judith Blake, Ti-Cheng Chang, Zhangzhi Hu, Hongfang Liu, Barry Smith, and Cathy H. Wu, "Framework for a Protein Ontology", Proceedings of the First International Workshop on Text Mining in Bioinformatics, 2006, p. 29-36.

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