Difference between revisions of "PRO"

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(Protein Ontology Kick-Off Meeting)
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== Protein Ontology Kick-Off Meeting ==
 
== Protein Ontology Kick-Off Meeting ==
  
The inaugural meeting of the Protein Ontology project will take place in Georgetown University on November 7-9, 2007. This is an internal meeting. Its goals are: to subject the PRO ontology to preliminary critique, and to establish plans for its further development, dissemination and use.
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The inaugural meeting of the Protein Ontology project will take place in Georgetown University, Washington DC on December 2-4, 2007. This is an internal meeting. Its goals are: to subject the PRO ontology to preliminary critique, and to establish plans for its further development, dissemination and use.
  
 
A draft program is as follows (names of proposed moderators for each session are given in parentheses):
 
A draft program is as follows (names of proposed moderators for each session are given in parentheses):
  
'''Date to be determined'''
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'''December 2'''
 
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Day 1
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Arrival of Workshop Participants
 
Arrival of Workshop Participants
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Dinner for Workshop Participants  
 
Dinner for Workshop Participants  
  
Day 2
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'''December 3'''
  
 
8:30am Continental Breakfast
 
8:30am Continental Breakfast
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6:00pm Dinner [Location to be Announced]
 
6:00pm Dinner [Location to be Announced]
  
Day 3
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'''December 4'''
 
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Location: ??
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8:30am Continental Breakfast
 
8:30am Continental Breakfast

Revision as of 11:20, 3 August 2007

Protein Ontology Kick-Off Meeting

The inaugural meeting of the Protein Ontology project will take place in Georgetown University, Washington DC on December 2-4, 2007. This is an internal meeting. Its goals are: to subject the PRO ontology to preliminary critique, and to establish plans for its further development, dissemination and use.

A draft program is as follows (names of proposed moderators for each session are given in parentheses):

December 2

Arrival of Workshop Participants

Dinner for Workshop Participants

December 3

8:30am Continental Breakfast

9:00am-10:30am Session 1: Introduction to the Protein Ontology (Cathy Wu)

10:45am-12:15pm Session 2: The Protein Ontology and Its Neighbors (Darren Natale)

12:15pm- 1:30pm Lunch

1:30pm- 3:00pm Session 3: The Protein Ontology within the OBO Foundry (Barry Smith)

3:30pm- 5:00pm Session 4: Protein Ontology and Protein Data (Chris Mungall and Alan Ruttenberg)

6:00pm Dinner [Location to be Announced]

December 4

8:30am Continental Breakfast

9:00am-10:30am Session 5: The Protein Ontology and Its Users 1 (Helen Berman)

10:45am-12:15pm Session 6: The Protein Ontology and Its Users 2 (Judith Blake)

1:30pm- 4:00pm Session 8: Next Steps (Suzanna Lewis)



Protein Ontology Specific Aims

The Protein Ontology (PRO) project is funded by NIGMS / NIH Grant 1 R01 GM080646-01, PI: Cathy Wu.

The Aims of the project are:

Aim 1. Develop a Protein Evolution (ProEvo) ontology to describe proteins based on evolutionary relationships. In essence, ProEvo will reflect protein families (using sequence or structure similarities) in an ontology framework.

Aim 2. Develop a Protein Forms (ProForm) ontology to represent the multiple protein end-products from a gene. This will include "normal" and mutant forms, forms derived from different splice variants, and cleaved and post-translationally modified products.

Aim 3. Specify the relationships between the ProEvo, ProMod and other OBO Foundry ontologies. Several ontologies provide qualities that can be attributed to various forms of a protein or to an entire protein family. These qualities, in effect, can annotate the protein forms or families.

Aim 4. Disseminate PRO ontology, and demonstrate its usefulness in health-related research via scientific case studies.


Literature

Darren A. Natale, Cecilia N. Arighi, Winona Barker, Judith Blake, Ti-Cheng Chang, Zhangzhi Hu, Hongfang Liu, Barry Smith, and Cathy H. Wu, "Framework for a Protein Ontology", Proceedings of the First International Workshop on Text Mining in Bioinformatics, 2006, p. 29-36.[1]

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